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| ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infection 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 17 作者: Mena E.L.; Donahue C.J.; Vaites L.P.; Li J.; Rona G.; O'Leary C.; Lignitto L.; Miwatani-Minter B.; Paulo J.A.; Dhabaria A.; Ueberheide B.; Gygi S.P.; Pagano M.; Harper J.W.; Davey R.A.; Elledge S.J. 收藏  |  浏览/下载:25/0  |  提交时间:2021/05/24 |
| Heteromeric HSFA2/HSFA3 complexes drive transcriptional memory after heat stress in Arabidopsis 期刊论文 Nature Communications, 2021, 卷号: 12, 期号: 1 作者: Friedrich T.; Oberkofler V.; Trindade I.; Altmann S.; Brzezinka K.; Lämke J.; Gorka M.; Kappel C.; Sokolowska E.; Skirycz A.; Graf A.; Bäurle I. 收藏  |  浏览/下载:37/0  |  提交时间:2022/02/22 |
| Expression attenuation as a mechanism of robustness against gene duplication 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 6 作者: Ascencio D.; Diss G.; Gagnon-Arsenault I.; Dubé A.K.; DeLuna A.; Landry C.R. 收藏  |  浏览/下载:32/0  |  提交时间:2021/05/24 |
| EIN3 and RSL4 interfere with an MYB–bHLH–WD40 complex to mediate ethylene-induced ectopic root hair formation in Arabidopsis 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 51 作者: Qiu Y.; Tao R.; Feng Y.; Xiao Z.; Zhang D.; Peng Y.; Wen X.; Wang Y.; Guo H. 收藏  |  浏览/下载:38/0  |  提交时间:2022/02/22 |
| High-throughput suppressor screen demonstrates that RcsF monitors outer membrane integrity and not Bam complex function 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 32 作者: Tata M.; Kumar S.; Lach S.R.; Saha S.; Hart E.M.; Konovalova A. 收藏  |  浏览/下载:46/0  |  提交时间:2022/02/22 |
| RNA-bound PGC-1α controls gene expression in liquid-like nuclear condensates 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 36 作者: Pérez-Schindler J.; Kohl B.; Schneider-Heieck K.; Leuchtmann A.B.; Henríquez-Olguín C.; Adak V.; Maier G.; Delezie J.; Sakoparnig T.; Vargas-Fernández E.; Karrer-Cardel B.; Ritz D.; Schmidt A.; Hondele M.; Jensen T.E.; Hiller S.; Handschin C. 收藏  |  浏览/下载:29/0  |  提交时间:2022/02/22 |
| Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文 , 2020, 卷号: 368, 期号: 6498 作者: Yin W.; Mao C.; Luan X.; Shen D.-D.; Shen Q.; Su H.; Wang X.; Zhou F.; Zhao W.; Gao M.; Chang S.; Xie Y.-C.; Tian G.; Jiang H.-W.; Tao S.-C.; Shen J.; Jiang Y.; Jiang H.; Xu Y.; Zhang S.; Zhang Y.; Xu H.E. 收藏  |  浏览/下载:189/0  |  提交时间:2020/07/28 adenosine phosphate alanine antivirus agent enzyme inhibitor multiprotein complex NSP7 protein, SARS-CoV-2 NSP8 protein, SARS-CoV-2 remdesivir RNA directed RNA polymerase RNA-dependent RNA polymerase, coronavirus viral protein virus RNA Betacoronavirus chemistry cryoelectron microscopy drug effect enzyme active site enzymology metabolism molecular model physiology protein conformation virus replication Adenosine Monophosphate Alanine Antiviral Agents Betacoronavirus Catalytic Domain Cryoelectron Microscopy Enzyme Inhibitors Models, Molecular Multiprotein Complexes Protein Conformation RNA Replicase RNA, Viral Viral Nonstructural Proteins Virus Replication |
| Metabolomics and mass spectrometry imaging reveal channeled de novo purine synthesis in cells 期刊论文 , 2020, 卷号: 368, 期号: 6488 作者: Pareek V.; Tian H.; Winograd N.; Benkovic S.J. 收藏  |  浏览/下载:32/0  |  提交时间:2020/07/28 adenosine phosphate guanosine phosphate multienzyme complex nucleotide purine purine purine derivative cell experimental study imaging method mass spectrometry metabolism protein Article biochemistry enzyme assay gas cluster ion beam secondary ion mass spectrometry image analysis mass spectrometry metabolomics mitochondrion molecular imaging molecular probe priority journal purine synthesis reaction analysis single cell analysis biosynthesis fluorescence imaging HeLa cell line human metabolism metabolomics procedures secondary ion mass spectrometry HeLa Cells Humans Metabolomics Mitochondria Multienzyme Complexes Optical Imaging Purines Single-Cell Analysis Spectrometry, Mass, Secondary Ion |
| Structural basis for strand-transfer inhibitor binding to HIV intasomes 期刊论文 , 2020, 卷号: 367, 期号: 6479 作者: Passos D.O.; Li M.; Jóźwik I.K.; Zhao X.Z.; Santos-Martins D.; Yang R.; Smith S.J.; Jeon Y.; Forli S.; Hughes S.H.; Burke T.R.; Jr.; Craigie R.; Lyumkis D. 收藏  |  浏览/下载:26/0  |  提交时间:2020/07/28 bictegravir nucleoprotein protein intasome unclassified drug viral protein bictegravir fused heterocyclic rings integrase integrase inhibitor multiprotein complex naphthyridine derivative nucleoprotein biochemistry chemical binding human immunodeficiency virus inhibitor protein ultrastructure amino terminal sequence Article carboxy terminal sequence catalysis cryoelectron microscopy drug design drug efficacy drug protein binding drug resistance drug structure enzyme active site human Human immunodeficiency virus infection nonhuman priority journal protein purification protein structure antiviral resistance chemistry drug effect genetics Human immunodeficiency virus virus DNA cell DNA interaction Cryoelectron Microscopy Drug Design Drug Resistance, Viral Heterocyclic Compounds, 4 or More Rings HIV HIV Integrase HIV Integrase Inhibitors Humans Multiprotein Complexes Naphthyridines Nucleoproteins Virus Integration |
| Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells 期刊论文 , 2020, 卷号: 368, 期号: 6493 作者: Bálint Š.; Müller S.; Fischer R.; Kessler B.M.; Harkiolaki M.; Valitutti S.; Dustin M.L. 收藏  |  浏览/下载:45/0  |  提交时间:2020/07/28 cancer cell identification method molecular analysis reconstruction granzyme multiprotein complex perforin thrombospondin 1 CRISPR Cas system cytotoxic T lymphocyte cytotoxicity exocytosis gene editing genetics human K-562 cell line metabolism x-ray tomography CRISPR-Cas Systems Cytotoxicity, Immunologic Exocytosis Gene Editing Granzymes Humans K562 Cells Multiprotein Complexes Perforin T-Lymphocytes, Cytotoxic Thrombospondin 1 Tomography, X-Ray |