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Massively multiplex chemical transcriptomics at single-cell resolution 期刊论文
, 2020, 卷号: 367, 期号: 6473
作者:  Srivatsan S.R.;  McFaline-Figueroa J.L.;  Ramani V.;  Saunders L.;  Cao J.;  Packer J.;  Pliner H.A.;  Jackson D.L.;  Daza R.M.;  Christiansen L.;  Zhang F.;  Steemers F.;  Shendure J.;  Trapnell C.
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/28
4 (2 aminoethylamino) 1,8 dimethylimidazo[1,2 a]quinoxaline  abexinostat  acetic acid  belinostat  cudc 101  fimepinostat  givinostat  histone deacetylase inhibitor  m 344  n [2 [3 (1 piperazinylmethyl)imidazo[2,1 b]thiazol 6 yl]phenyl] 2 quinoxalinecarboxamide  panobinostat  pracinostat  rec 2282  trametinib  transcriptome  trichostatin A  unclassified drug  transcriptome  cancer  cell  chemical analysis  detection method  experimental study  genetic analysis  resolution  A-549 cell line  animal cell  animal experiment  Article  cell function  cell heterogeneity  cell labeling  cell proliferation  chromatin  controlled study  dose response  drug activity  experimentation  gene control  genetic transcription  human  human cell  K-562 cell line  MCF-7 cell line  mouse  nonhuman  pilot study  priority journal  proof of concept  RNA sequence  screening  single cell analysis  transcriptomics  cell nucleus  drug effect  genetics  genomics  high throughput screening  metabolism  neoplasm  procedures  single cell analysis  A549 Cells  Acetates  Cell Nucleus  Chromatin  Genomics  High-Throughput Screening Assays  Histone Deacetylase Inhibitors  Humans  K562 Cells  MCF-7 Cells  Neoplasms  RNA-Seq  Single-Cell Analysis  Transcriptome  
Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells 期刊论文
, 2020, 卷号: 368, 期号: 6493
作者:  Bálint Š.;  Müller S.;  Fischer R.;  Kessler B.M.;  Harkiolaki M.;  Valitutti S.;  Dustin M.L.
收藏  |  浏览/下载:45/0  |  提交时间:2020/07/28
cancer  cell  identification method  molecular analysis  reconstruction  granzyme  multiprotein complex  perforin  thrombospondin 1  CRISPR Cas system  cytotoxic T lymphocyte  cytotoxicity  exocytosis  gene editing  genetics  human  K-562 cell line  metabolism  x-ray tomography  CRISPR-Cas Systems  Cytotoxicity, Immunologic  Exocytosis  Gene Editing  Granzymes  Humans  K562 Cells  Multiprotein Complexes  Perforin  T-Lymphocytes, Cytotoxic  Thrombospondin 1  Tomography, X-Ray  
Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Battich N.;  Beumer J.;  De Barbanson B.;  Krenning L.;  Baron C.S.;  Tanenbaum M.E.;  Clevers H.;  Van Oudenaarden A.
收藏  |  浏览/下载:174/0  |  提交时间:2020/07/28
messenger RNA  dyes, reagents, indicators, markers and buffers  messenger RNA  uridine  cell component  differentiation  gene expression  metabolism  RNA  turnover  Article  cell cycle  cell differentiation  cell metabolism  gene cluster  gene control  gene expression  genetic transcription  human  intestinal stem cell  molecular dynamics  priority journal  regulatory mechanism  RNA sequencing  single cell analysis  animal  chemistry  K-562 cell line  metabolism  mouse  procedures  RNA stability  sequence analysis  single cell analysis  Mammalia  Animals  Humans  Indicators and Reagents  K562 Cells  Mice  RNA Stability  RNA, Messenger  Sequence Analysis, RNA  Single-Cell Analysis  Transcription, Genetic  Uridine