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Chang R. [2]
Kim J.H. [2]
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文献类型
期刊论文 [42]
发表日期
2020 [42]
语种
英语 [42]
来源机构
Science [42]
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CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation
期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:
Muendlein H.I.
;
Jetton D.
;
Connolly W.M.
;
Eidell K.P.
;
Magri Z.
;
Smirnova I.
;
Poltorak A.
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/28
FLICE inhibitory protein
interleukin 1beta
lipopolysaccharide
messenger RNA
succinate dehydrogenase (ubiquinone)
Casp1 protein, mouse
caspase 8
Cflar protein, mouse
cryopyrin
FLICE inhibitory protein
IL1B protein, mouse
inflammasome
interleukin 1beta
interleukin 1beta converting enzyme
lipopolysaccharide
succinate dehydrogenase (ubiquinone)
cell
enzyme activity
inhibition
maturation
protein
animal cell
animal experiment
Article
bone marrow derived macrophage
cell death
cell protection
complex formation
controlled study
cytokine release
in vitro study
inflammation
mouse
nonhuman
priority journal
protein analysis
protein degradation
protein function
protein interaction
pyroptosis
animal
gene knockdown
genetics
immunology
macrophage
macrophage activation
metabolism
physiology
Murinae
Animals
CASP8 and FADD-Like Apoptosis Regulating Protein
Caspase 1
Caspase 8
Electron Transport Complex II
Gene Knockdown Techniques
Inflammasomes
Interleukin-1beta
Lipopolysaccharides
Macrophage Activation
Macrophages
Mice
NLR Family, Pyrin Domain-Containing 3 Protein
Pyroptosis
T cells with dysfunctional mitochondria induce multimorbidity and premature senescence
期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:
Desdín-Micó G.
;
Soto-Heredero G.
;
Aranda J.F.
;
Oller J.
;
Carrasco E.
;
Gabandé-Rodríguez E.
;
Blanco E.M.
;
Alfranca A.
;
Cussó L.
;
Desco M.
;
Ibañez B.
;
Gortazar A.R.
;
Fernández-Marcos P.
;
Navarro M.N.
;
Hernaez B.
;
Alcamí A.
;
Baixauli F.
;
Mittelbrunn M.
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/28
cardiovascular disease
enzyme activity
gene expression
metabolism
mitochondrial DNA
morbidity
senescence
tumor
Mus
DNA binding protein
mitochondrial protein
mitochondrial transcription factor A
nicotinamide adenine dinucleotide
transcription factor
tumor necrosis factor
animal
cytokine release syndrome
female
fitness
gene deletion
genetics
immunology
inflammation
longevity
male
metabolism
mitochondrion
mouse
multiple chronic conditions
mutant mouse strain
premature aging
T lymphocyte
ultrastructure
Aging, Premature
Animals
Cytokine Release Syndrome
DNA-Binding Proteins
Female
Gene Deletion
Inflammation
Longevity
Male
Mice
Mice, Mutant Strains
Mitochondria
Mitochondrial Proteins
Multimorbidity
NAD
Physical Fitness
T-Lymphocytes
Transcription Factors
Tumor Necrosis Factor-alpha
Membrane-proximal F-actin restricts local membrane protrusions and directs cell migration
期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:
Bisaria A.
;
Hayer A.
;
Garbett D.
;
Cohen D.
;
Meyer T.
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/28
cell component
concentration (composition)
membrane
polymerization
protein
actin
green fluorescent protein
cell membrane
cell motion
cell polarity
cell surface
chemistry
genetics
human
metabolism
umbilical vein endothelial cell
Actins
Cell Membrane
Cell Movement
Cell Polarity
Cell Surface Extensions
Green Fluorescent Proteins
Human Umbilical Vein Endothelial Cells
Humans
Temporal integration of mitogen history in mother cells controls proliferation of daughter cells
期刊论文
, 2020, 卷号: 368, 期号: 6496
作者:
Min M.
;
Rong Y.
;
Tian C.
;
Spencer S.L.
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/28
cyclin D
mitogen activated protein kinase kinase
mitogenic agent
cell cycle G1 phase
cell cycle G2 phase
cell proliferation
genetics
human
metabolism
physiology
protein synthesis
signal transduction
stem cell
Cell Proliferation
Cyclin D
G1 Phase
G2 Phase
Humans
Mitogen-Activated Protein Kinase Kinases
Mitogens
Protein Biosynthesis
Signal Transduction
Stem Cells
Structure of the RNA-dependent RNA polymerase from COVID-19 virus
期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:
Gao Y.
;
Yan L.
;
Huang Y.
;
Liu F.
;
Zhao Y.
;
Cao L.
;
Wang T.
;
Sun Q.
;
Ming Z.
;
Zhang L.
;
Ge J.
;
Zheng L.
;
Zhang Y.
;
Wang H.
;
Zhu Y.
;
Zhu C.
;
Hu T.
;
Hua T.
;
Zhang B.
;
Yang X.
;
Li J.
;
Yang H.
;
Liu Z.
;
Xu W.
;
Guddat L.W.
;
Wang Q.
;
Lou Z.
;
Rao Z.
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/28
comparative study
drug
electron microscopy
enzyme
enzyme activity
RNA
virus
Coronavirus
SARS coronavirus
adenosine phosphate
alanine
antivirus agent
NSP7 protein, SARS-CoV-2
NSP8 protein, SARS-CoV-2
remdesivir
RNA directed RNA polymerase
RNA-dependent RNA polymerase, coronavirus
viral protein
beta sheet
Betacoronavirus
chemistry
cryoelectron microscopy
drug design
enzyme active site
enzymology
metabolism
molecular model
protein domain
ultrastructure
Adenosine Monophosphate
Alanine
Antiviral Agents
Betacoronavirus
Catalytic Domain
Cryoelectron Microscopy
Drug Design
Models, Molecular
Protein Conformation, beta-Strand
Protein Domains
RNA Replicase
Viral Nonstructural Proteins
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Guthrie L.M.
;
Soma S.
;
Yuan S.
;
Silva A.
;
Zulkifli M.
;
Snavely T.C.
;
Greene H.F.
;
Nunez E.
;
Lynch B.
;
de Ville C.
;
Shanbhag V.
;
Lopez F.R.
;
Acharya A.
;
Petris M.J.
;
Kim B.-E.
;
Gohil V.M.
;
Sacchettini J.C.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/28
copper
copper zinc superoxide dismutase
cytochrome c oxidase
dopamine beta monooxygenase
elesclomol
monophenol monooxygenase
protein lysine 6 oxidase
copper
cytochrome c oxidase
elesclomol
hydrazine derivative
copper
cytochrome
enzyme
enzyme activity
mitochondrion
mortality
mutation
pathology
rodent
survival
animal cell
animal experiment
animal model
animal tissue
Article
cohort analysis
controlled study
disease severity
drug mechanism
Golgi complex
H9c2(2-1) cell line
in vivo study
male
Menkes syndrome
mitochondrial dynamics
mortality rate
mouse
nerve degeneration
nonhuman
priority journal
secretory pathway
survival rate
animal
brain
cell line
degenerative disease
disease model
drug effect
genetics
knockout mouse
Menkes syndrome
metabolism
mitochondrion
pathology
rat
transport at the cellular level
Murinae
Mus
Animals
Biological Transport
Brain
Cell Line
Copper
Copper Transporter 1
Disease Models, Animal
Electron Transport Complex IV
Hydrazines
Male
Menkes Kinky Hair Syndrome
Mice
Mice, Knockout
Mitochondria
Neurodegenerative Diseases
Rats
Transcription polymerase-catalyzed emergence of novel RNA replicons
期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:
Jain N.
;
Blauch L.R.
;
Szymanski M.R.
;
Das R.
;
Tang S.K.Y.
;
Yin Y.W.
;
Fire A.Z.
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/28
cell component
enzyme
enzyme activity
genetic analysis
RNA
article
bacteriophage
catalysis
DNA replication origin
heredity
in vitro study
nonhuman
plant seed
replicon
RNA replication
synthesis
transcription initiation
biocatalysis
biosynthesis
genetic transcription
metabolism
Animalia
Hepatitis delta virus
Viroids
bacteriophage T7 RNA polymerase
DNA directed RNA polymerase
RNA
viral protein
Biocatalysis
DNA-Directed RNA Polymerases
Replicon
RNA
Transcription, Genetic
Viral Proteins
Microenvironment mapping via Dexter energy transfer on immune cells
期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:
Geri J.B.
;
Oakley J.V.
;
Reyes-Robles T.
;
Wang T.
;
McCarver S.J.
;
White C.H.
;
Rodriguez-Rivera F.P.
;
Parker D.L.
;
Hett E.C.
;
Fadeyi O.O.
;
Oslund R.C.
;
MacMillan D.W.C.
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/28
antibody conjugate
carbene
programmed death 1 ligand 1
methane
programmed death 1 ligand 1
antibody
catalysis
catalyst
cell component
detection method
enzyme
enzyme activity
protein
antigen binding
Article
cell membrane
energy transfer
human
immunocompetent cell
immunological synapse
lymphocyte
photocatalysis
priority journal
protein analysis
protein protein interaction
tumor microenvironment
catalysis
chemistry
energy transfer
Jurkat cell line
metabolism
photochemistry
procedures
radiation response
ultraviolet radiation
B7-H1 Antigen
Catalysis
Cell Membrane
Cellular Microenvironment
Energy Transfer
Humans
Jurkat Cells
Lymphocytes
Methane
Photochemical Processes
Protein Interaction Mapping
Protein Interaction Maps
Ultraviolet Rays
PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis
期刊论文
, 2020, 卷号: 367, 期号: 6482
作者:
Wang Q.
;
Boshoff H.I.M.
;
Harrison J.R.
;
Ray P.C.
;
Green S.R.
;
Wyatt P.G.
;
Barry Iii C.E.
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/28
3,3 bis di(methylsulfonyl)propionamide
antiinfective agent
bacterial protein
glucose
glycerol
magnesium
phosphate
propionamide derivative
protein proline proline glutamate
protein proline proline glutamate 51
unclassified drug
amide
bacterial protein
lipid
phthiocerol dimycocerosate
propionamide
thiol derivative
cell component
chemical compound
membrane
mutation
protein
tuberculosis
antibiotic resistance
Article
bacterial cell
bacterial cell wall
bacterial growth
bacterial outer membrane
cell division
drug structure
Mycobacterium tuberculosis
nonhuman
nutrient uptake
priority journal
protein depletion
cell membrane
cell membrane permeability
chemistry
drug effect
gene deletion
genetics
metabolism
transport at the cellular level
Mycobacterium tuberculosis
Amides
Bacterial Proteins
Biological Transport
Cell Membrane
Cell Membrane Permeability
Drug Resistance, Bacterial
Gene Deletion
Glucose
Glycerol
Lipids
Mycobacterium tuberculosis
Sulfhydryl Compounds
Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b
期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:
Weber C.
;
Zhou Y.
;
Lee J.G.
;
Looger L.L.
;
Qian G.
;
Ge C.
;
Capel B.
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/28
STAT3 protein
calcium
histone demethylase
STAT3 protein
embryonic development
gene expression
sex determination
temperature effect
turtle
animal cell
animal experiment
Article
binding site
calcium transport
cell activation
chromatin immunoprecipitation
controlled study
dimerization
Dmrt1 gene
embryo
embryo development
environmental temperature
epigenetic repression
female
gene
gene activation
gene interaction
gene targeting
genetic transcription
gonad
high temperature
immunofluorescence test
Kdm6b gene
male
nonhuman
priority journal
protein phosphorylation
real time polymerase chain reaction
sex determination
signal transduction
temperature dependence
thermoregulation
transcription regulation
upregulation
Western blotting
animal
embryology
gene expression regulation
genetics
metabolism
phosphorylation
sex determination process
temperature
turtle
Reptilia
Trachemys scripta
Trachemys scripta elegans
Animals
Calcium
Female
Gene Expression Regulation, Developmental
Jumonji Domain-Containing Histone Demethylases
Male
Phosphorylation
Sex Determination Processes
STAT3 Transcription Factor
Temperature
Transcription, Genetic
Turtles