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Evaluating biological activity of compounds by transcription factor activity profiling 期刊论文
SCIENCE ADVANCES, 2018, 卷号: 4, 期号: 9
作者:  Medvedev, Alexander;  Moeser, Matt;  Medvedeva, Liubov;  Martsen, Elena;  Granick, Alexander;  Raines, Lydia;  Zeng, Ming;  Makarov, Sergei, Jr.;  Houck, Keith A.;  Makarov, Sergei S.
收藏  |  浏览/下载：20/0  |  提交时间：2019/05/04
Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2018, 卷号: 126, 期号: 7
作者:  Xia, Menghang;  Huang, Ruili;  Shi, Qiang;  Boyd, Windy A.;  Zhao, Jinghua;  Sun, Nuo;  Rice, Julie R.;  Dunlap, Paul E.;  Hackstadt, Amber J.;  Bridge, Matt F.;  Smith, Marjolein V.;  Dai, Sheng;  Zheng, Wei;  Chu, Pei-Hsuan;  Gerhold, David;  Witt, Kristine L.;  DeVito, Michael;  Freedman, Jonathan H.;  Austin, Christopher P.;  Houck, Keith A.;  Thomas, Russell S.;  Paules, Richard S.;  Tice, Raymond R.;  Simeonov, Anton
收藏  |  浏览/下载：54/0  |  提交时间：2019/05/04
Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:  Mahapatra, Debabrata;  Franzosa, Jill A.;  Roell, Kyle;  Kuenemann, Melaine Agnes;  Houck, Keith A.;  Reif, David M.;  Fourches, Denis;  Kullman, Seth W.
收藏  |  浏览/下载：34/0  |  提交时间：2019/05/04
Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates 期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 1, 页码: 487-500
作者:  Strickland, Jenna D.;  Martin, Matthew T.;  Richard, Ann M.;  Houck, Keith A.;  Shafer, Timothy J.
收藏  |  浏览/下载：23/0  |  提交时间：2019/05/04
On selecting a minimal set of in vitro assays to reliably determine estrogen agonist activity 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2017, 卷号: 91, 页码: 39-49
作者:  Judson, Richard S.;  Houck, Keith A.;  Watt, Eric D.;  Thomas, Russell S.
收藏  |  浏览/下载：30/0  |  提交时间：2019/05/04
The benefits of data mining Careful analysis of a database populated by physicians and patients sheds new light on the side effects of drugs 期刊论文
ELIFE, 2017, 卷号: 6
作者:  Bone, Audrey;  Houck, Keith
收藏  |  浏览/下载：16/0  |  提交时间：2019/05/04
An "EAR" on Environmental Surveillance and Monitoring: A Case Study on the Use of Exposure Activity Ratios (EARs) to Prioritize Sites, Chemicals, and Bioactivities of Concern in Great Lakes Waters 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 卷号: 51, 期号: 15, 页码: 8713-8724
作者:  Blackwell, Brett R.;  Ankley, Gerald T.;  Corsi, Steven R.;  DeCicco, Laura A.;  Houck, Keith A.;  Judson, Richard S.;  Li, Shibin;  Martin, Matthew T.;  Murphy, Elizabeth;  Schroeder, Anthony L.;  Smith, Edwin R.;  Swintek, Joe;  Villeneuve, Daniel L.
收藏  |  浏览/下载：29/0  |  提交时间：2019/05/04
Primary Cell Phenotypic Screening Illuminates ADRs and AOPs 期刊论文
CELL CHEMICAL BIOLOGY, 2017, 卷号: 24, 期号: 7, 页码: 781-782
作者:  Bone, Audrey J.;  Houck, Keith A.
收藏  |  浏览/下载：27/0  |  提交时间：2019/05/04
Identifying environmental chemicals as agonists of the androgen receptor by using a quantitative high-throughput screening platform 期刊论文
TOXICOLOGY, 2017, 卷号: 385, 页码: 48-58
作者:  Lynch, Caitlin;  Sakamuru, Srilatha;  Huang, Ruili;  Stavreva, Diana A.;  Varticovski, Lyuba;  Hager, Gordon L.;  Judson, Richard S.;  Houck, Keith A.;  Kleinstreuer, Nicole C.;  Casey, Warren;  Paules, Richard S.;  Simeonov, Anton;  Xia, Menghang
收藏  |  浏览/下载：33/0  |  提交时间：2019/05/04
Development and Validation of a Computational Model for Androgen Receptor Activity 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2017, 卷号: 30, 期号: 4, 页码: 946-964
作者:  Kleinstreuer, Nicole C.;  Ceger, Patricia;  Watt, Eric D.;  Martin, Matthew;  Houck, Keith;  Browne, Patience;  Thomas, Russell S.;  Casey, Warren M.;  Dix, David J.;  Allen, David;  Sakamuru, Srilatha;  Xia, Menghang;  Huang, Ruili;  Judson, Richard
收藏  |  浏览/下载：33/0  |  提交时间：2019/05/04