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| A Novel Approach to Carrying Capacity: From a priori Prescription to a posteriori Derivation Based on Underlying Mechanisms and Dynamics 期刊论文
, 2020, 卷号: 48
作者: Mote S.; Rivas J.; Kalnay E.
  收藏 | 浏览/下载：39/0 | 提交时间：2020/07/28
Dynamics Sustainable development Bidirectional coupling Earth systems Human population Human system Logistic equations Minimal model New approaches Priori prescriptions Fossil fuels carrying capacity fossil fuel numerical model sustainability |
| A neurodevelopmental origin of behavioral individuality in the Drosophila visual system 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者: Linneweber G.A.; Andriatsilavo M.; Dutta S.B.; Bengochea M.; Hellbruegge L.; Liu G.; Ejsmont R.K.; Straw A.D.; Wernet M.; Hiesinger P.R.; Hassan B.A.
收藏 | 浏览/下载：50/0 | 提交时间：2020/07/28
anatomy asymmetry brain genome neurology orientation visual analysis article brain Drosophila melanogaster human experiment individuality nerve cell nonhuman stochastic model visual system walking anatomy and histology animal Drosophila melanogaster genetic variation genetics growth, development and aging nervous system development orientation physiology visual field visual system Drosophila melanogaster Animals Brain Drosophila melanogaster Genetic Variation Individuality Neurogenesis Orientation Visual Fields Visual Pathways |
| Pervasive functional translation of noncanonical human open reading frames 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者: Chen J.; Brunner A.-D.; Cogan J.Z.; Nuñez J.K.; Fields A.P.; Adamson B.; Itzhak D.N.; Li J.Y.; Mann M.; Leonetti M.D.; Weissman J.S.
收藏 | 浏览/下载：31/0 | 提交时间：2020/07/28
messenger RNA peptide transcriptome CRISPR Cas system genetics human metabolism open reading frame operon protein synthesis ribosome CRISPR-Cas Systems Humans Open Reading Frames Operon Peptides Protein Biosynthesis Ribosomes RNA, Messenger Transcriptome |
| Overcoming obstacles to experiments in legall practice 期刊论文
, 2020, 卷号: 367, 期号: 6482
作者: Lynch H.F.; Greiner D.J.; Cohen I.G.
收藏 | 浏览/下载：38/0 | 提交时间：2020/07/28
experiment legal system policy approach research Article clinical research criminal justice domestic violence ethics evidence based practice health care quality human jurisprudence legal aspect legal service medical profession patient care politics priority journal public policy randomization social responsibility social support |
| Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants 期刊论文
, 2020, 卷号: 368, 期号: 6488
作者: Walton R.T.; Christie K.A.; Whittaker M.N.; Kleinstiver B.P.
收藏 | 浏览/下载：27/0 | 提交时间：2020/07/28
adenine adenosine CRISPR associated endonuclease Cas9 cytosine guanosine SpG protein SpRY nuclease thymine unclassified drug Cas9 endonuclease Streptococcus pyogenes bacterium enzyme activity genetic engineering genetic variation genome Article CRISPR-CAS9 system DNA sequence enzyme activity gene editing gene targeting genetic variability human mutagenesis nonhuman priority journal protein engineering protein motif protein structure protospacer adjacent motif Streptococcus pyogenes chemistry CRISPR Cas system enzyme specificity gene editing gene targeting genetic predisposition genetics HEK293 cell line procedures protein domain Streptococcus pyogenes CRISPR-Associated Protein 9 CRISPR-Cas Systems Gene Editing Gene Targeting Genetic Predisposition to Disease HEK293 Cells Humans Mutagenesis Protein Domains Substrate Specificity |
| Single-cell transcriptional diversity is a hallmark of developmental potential 期刊论文
, 2020, 卷号: 367, 期号: 6476
作者: Gulati G.S.; Sikandar S.S.; Wesche D.J.; Manjunath A.; Bharadwaj A.; Berger M.J.; Ilagan F.; Kuo A.H.; Hsieh R.W.; Cai S.; Zabala M.; Scheeren F.A.; Lobo N.A.; Qian D.; Yu F.B.; Dirbas F.M.; Clarke M.F.; Newman A.M.
收藏 | 浏览/下载：47/0 | 提交时间：2020/07/28
cell cell component developmental biology experimental study genetic analysis tumor Article breast cancer breast carcinogenesis carcinogenesis cell differentiation computer model embryonic stem cell gene expression genetic code genetic variability human in vivo study nonhuman phenotype priority journal scoring system single cell RNA seq upregulation |
| Poised for tissue repair 期刊论文
, 2020, 卷号: 369, 期号: 6500
作者: Harrison O.
收藏 | 浏览/下载：42/0 | 提交时间：2020/07/28
CD8+ T lymphocyte human immune system immunology microbiology microflora skin Staphylococcus epidermidis symbiosis wound healing CD8-Positive T-Lymphocytes Humans Immune System Microbiota Skin Staphylococcus epidermidis Symbiosis Wound Healing |
| Modulating microbiome metabolites in vivo 期刊论文
, 2020, 卷号: 369, 期号: 6500
作者: Guo C.-J.
收藏 | 浏览/下载：22/0 | 提交时间：2020/07/28
Clostridium CRISPR Cas system genetics human intestine flora metabolism Clostridium CRISPR-Cas Systems Gastrointestinal Microbiome Host Microbial Interactions Humans |
| Very fast CRISPR on demand 期刊论文
, 2020, 卷号: 368, 期号: 6496
作者: Liu Y.; Zou R.S.; He S.; Nihongaki Y.; Li X.; Razavi S.; Wu B.; Ha T.
收藏 | 浏览/下载：38/0 | 提交时间：2020/07/28
Cas9 endonuclease Streptococcus pyogenes double strand break repair protein MRE11 H2AX protein, human histone MRE11 protein, human CRISPR Cas system DNA cleavage DNA repair double stranded DNA break fluorescence imaging gene editing genetics HEK293 cell line human light metabolism phosphorylation procedures radiation response single cell analysis CRISPR-Associated Protein 9 CRISPR-Cas Systems DNA Breaks, Double-Stranded DNA Cleavage DNA Repair Gene Editing HEK293 Cells Histones Humans Light MRE11 Homologue Protein Optical Imaging Phosphorylation Single-Cell Analysis |
| Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing 期刊论文
, 2020, 卷号: 368, 期号: 6491
作者: Ferretti L.; Wymant C.; Kendall M.; Zhao L.; Nurtay A.; Abeler-Dörner L.; Parker M.; Bonsall D.; Fraser C.
收藏 | 浏览/下载：32/0 | 提交时间：2020/07/28
disease control epidemic memory parasite transmission viral disease Article asymptomatic disease China contact examination coronavirus disease 2019 disease control disease transmission health care system human incubation time mathematical model mobile application mortality rate priority journal quarantine rating scale Severe acute respiratory syndrome coronavirus 2 virus transmission algorithm basic reproduction number Betacoronavirus contact examination Coronavirus infection epidemic ethics infection control mobile application mobile phone pandemic probability procedures theoretical model time factor virus pneumonia Coronavirus SARS coronavirus Algorithms Asymptomatic Diseases Basic Reproduction Number Betacoronavirus Cell Phone China Contact Tracing Coronavirus Infections Epidemics Humans Infection Control Mobile Applications Models, Theoretical Pandemics Pneumonia, Viral Probability Quarantine Time Factors |
