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Oncogenic lncRNA LINC00973 promotes warburg effect by enhancing LDHA enzyme activity 期刊论文
Science Bulletin, 2021
作者:  Wang H.;  Lin K.;  Zhu L.;  Zhang S.;  Li L.;  Liao Y.;  Zhang B.;  Yang M.;  Liu X.;  Li L.;  Li S.;  Yang L.;  Wang H.;  Wang Q.;  Li H.;  Fu S.;  Zhang X.;  Jiang P.;  Zhang Q.C.;  Cheng J.;  Wang D.
收藏  |  浏览/下载:54/0  |  提交时间:2021/09/01
Biomarker  Cancer metabolism  LDHA  LINC00973  Warburg effect  
Bacterial degradation of pyrene: Biochemical reactions and mechanisms 期刊论文
INTERNATIONAL BIODETERIORATION & BIODEGRADATION, 2021, 卷号: 162
作者:  Zada, Sahib;  Zhou, Haixin;  Xie, Jianmin;  Hu, Zhong;  Ali, Sardar;  Sajjad, Wasim;  Wang, Hui
收藏  |  浏览/下载:30/0  |  提交时间:2022/04/28
POLYCYCLIC AROMATIC-HYDROCARBONS  DEGRADING CONSORTIUM  SP NOV.  ANAEROBIC BIODEGRADATION  PAH DEGRADATION  NORTH-ATLANTIC  LUNG-CANCER  STRAIN  MARINE  METABOLISM  
Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice 期刊论文
, 2020, 卷号: 367, 期号: 6481
作者:  Kimura I.;  Miyamoto J.;  Ohue-Kitano R.;  Watanabe K.;  Yamada T.;  Onuki M.;  Aoki R.;  Isobe Y.;  Kashihara D.;  Inoue D.;  Inaba A.;  Takamura Y.;  Taira S.;  Kumaki S.;  Watanabe M.;  Ito M.;  Nakagawa F.;  Irie J.;  Kakuta H.;  Shinohara M.;  Iwatsuki K.;  Tsujimoto G.;  Ohno H.;  Arita M.;  Itoh H.;  Hase K.
收藏  |  浏览/下载:48/0  |  提交时间:2020/07/28
G protein coupled receptor  G protein coupled receptor 41  G protein coupled receptor 43  glucagon like peptide 1  short chain fatty acid  unclassified drug  disease incidence  experimental study  female  microbial community  phenotype  pregnancy  rodent  adult  animal cell  animal experiment  animal model  animal tissue  Article  C57BL 6 mouse  cell differentiation  controlled study  developmental stage  diet composition  diet supplementation  dietary exposure  disease exacerbation  disease predisposition  embryo  embryo development  energy metabolism  enteroendocrine cell  female  fiber intake  germfree animal  glucose intolerance  high risk pregnancy  hyperglycemia  Institute for Cancer Research mouse  insulin metabolism  intestine flora  lipid diet  low fiber diet  male  maternal nutrition  metabolic syndrome X  mouse  newborn  nonhuman  obesity  pancreas islet beta cell  phenotype  pregnancy  prenatal development  priority journal  progeny  protein expression  risk reduction  Mus  
Massively multiplex chemical transcriptomics at single-cell resolution 期刊论文
, 2020, 卷号: 367, 期号: 6473
作者:  Srivatsan S.R.;  McFaline-Figueroa J.L.;  Ramani V.;  Saunders L.;  Cao J.;  Packer J.;  Pliner H.A.;  Jackson D.L.;  Daza R.M.;  Christiansen L.;  Zhang F.;  Steemers F.;  Shendure J.;  Trapnell C.
收藏  |  浏览/下载:20/0  |  提交时间:2020/07/28
4 (2 aminoethylamino) 1,8 dimethylimidazo[1,2 a]quinoxaline  abexinostat  acetic acid  belinostat  cudc 101  fimepinostat  givinostat  histone deacetylase inhibitor  m 344  n [2 [3 (1 piperazinylmethyl)imidazo[2,1 b]thiazol 6 yl]phenyl] 2 quinoxalinecarboxamide  panobinostat  pracinostat  rec 2282  trametinib  transcriptome  trichostatin A  unclassified drug  transcriptome  cancer  cell  chemical analysis  detection method  experimental study  genetic analysis  resolution  A-549 cell line  animal cell  animal experiment  Article  cell function  cell heterogeneity  cell labeling  cell proliferation  chromatin  controlled study  dose response  drug activity  experimentation  gene control  genetic transcription  human  human cell  K-562 cell line  MCF-7 cell line  mouse  nonhuman  pilot study  priority journal  proof of concept  RNA sequence  screening  single cell analysis  transcriptomics  cell nucleus  drug effect  genetics  genomics  high throughput screening  metabolism  neoplasm  procedures  single cell analysis  A549 Cells  Acetates  Cell Nucleus  Chromatin  Genomics  High-Throughput Screening Assays  Histone Deacetylase Inhibitors  Humans  K562 Cells  MCF-7 Cells  Neoplasms  RNA-Seq  Single-Cell Analysis  Transcriptome  
Regenerative potential of prostate luminal cells revealed by single-cell analysis 期刊论文
, 2020, 卷号: 368, 期号: 6490
作者:  Karthaus W.R.;  Hofree M.;  Choi D.;  Linton E.L.;  Turkekul M.;  Bejnood A.;  Carver B.;  Gopalan A.;  Abida W.;  Laudone V.;  Biton M.;  Chaudhary O.;  Xu T.;  Masilionis I.;  Manova K.;  Mazutis L.;  Pe’er D.;  Regev A.;  Sawyers C.L.
收藏  |  浏览/下载:243/0  |  提交时间:2020/07/28
androgen  growth factor  Nrg2 growth factor  Rspo3 growth factor  unclassified drug  androgen binding protein  antiandrogen  ataxin 1  Atxn1 protein, mouse  glycosylphosphatidylinositol anchored protein  homeodomain protein  nerve growth factor  Nkx3-1 protein, mouse  Nrg2 protein, mouse  probasin  Psca protein, mouse  R-spondin3 protein, mouse  thrombospondin  transcription factor  tumor antigen  tumor protein  androgen  cancer  cell  gene expression  RNA  rodent  ablation therapy  animal cell  animal tissue  Article  cell differentiation  cell population  cell regeneration  cells by body anatomy  controlled study  gene  gene expression  human  luminal cell  male  mesenchyme cell  mouse  nonhuman  paracrine signaling  priority journal  prostate cell  prostate tissue  protein expression  Psca gene  RNA sequencing  Sca1 gene  single cell analysis  animal  genetics  mesenchymal stem cell  metabolism  organ size  organoid  physiology  prostate  prostate tumor  regeneration  sequence analysis  single cell analysis  Mus  Androgen Antagonists  Androgen-Binding Protein  Androgens  Animals  Antigens, Neoplasm  Ataxin-1  Cell Differentiation  Gene Expression  GPI-Linked Proteins  Homeodomain Proteins  Humans  Male  Mesenchymal Stem Cells  Mice  Neoplasm Proteins  Nerve Growth Factors  Organ Size  Organoids  Prostate  Prostatic Neoplasms  Regeneration  Sequence Analysis, RNA  Single-Cell Analysis  Thrombospondins  Transcription Factors  
Partitioning of cancer therapeutics in nuclear condensates 期刊论文
, 2020, 卷号: 368, 期号: 6497
作者:  Klein I.A.;  Boija A.;  Afeyan L.K.;  Hawken S.W.;  Fan M.;  Dall'Agnese A.;  Oksuz O.;  Henninger J.E.;  Shrinivas K.;  Sabari B.R.;  Sagi I.;  Clark V.E.;  Platt J.M.;  Kar M.;  McCall P.M.;  Zamudio A.V.;  Manteiga J.C.;  Coffey E.L.;  Li C.H.;  Hannett N.M.;  Guo Y.E.;  Decker T.-M.;  Lee T.I.;  Zhang T.;  Weng J.-K.;  Taatjes D.J.;  Chakraborty A.;  Sharp P.A.;  Chang Y.T.;  Hyman A.A.;  Gray N.S.;  Young R.A.
收藏  |  浏览/下载:40/0  |  提交时间:2020/07/28
cancer  condensate  disease  drug  physicochemical property  protein  tumor  antineoplastic agent  BRD4 protein, human  cell cycle protein  green fluorescent protein  heterochromatin-specific nonhistone chromosomal protein HP-1  MED1 protein, human  nonhistone protein  nuclear protein  nucleophosmin  peroxisome proliferator activated receptor binding protein  recombinant protein  serine arginine rich splicing factor  SRSF2 protein, human  transcription factor  cell nucleus  drug resistance  genetics  human  metabolism  neoplasm  Antineoplastic Agents  Cell Cycle Proteins  Cell Nucleus  Chromosomal Proteins, Non-Histone  Drug Resistance, Neoplasm  Green Fluorescent Proteins  Humans  Mediator Complex Subunit 1  Neoplasms  Nuclear Proteins  Recombinant Proteins  Serine-Arginine Splicing Factors  Transcription Factors  
Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells 期刊论文
, 2020, 卷号: 368, 期号: 6493
作者:  Bálint Š.;  Müller S.;  Fischer R.;  Kessler B.M.;  Harkiolaki M.;  Valitutti S.;  Dustin M.L.
收藏  |  浏览/下载:46/0  |  提交时间:2020/07/28
cancer  cell  identification method  molecular analysis  reconstruction  granzyme  multiprotein complex  perforin  thrombospondin 1  CRISPR Cas system  cytotoxic T lymphocyte  cytotoxicity  exocytosis  gene editing  genetics  human  K-562 cell line  metabolism  x-ray tomography  CRISPR-Cas Systems  Cytotoxicity, Immunologic  Exocytosis  Gene Editing  Granzymes  Humans  K562 Cells  Multiprotein Complexes  Perforin  T-Lymphocytes, Cytotoxic  Thrombospondin 1  Tomography, X-Ray