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World Trade Center Responders at Higher Risk for Blood Cancer-Associated Mutations, Study Finds 科技资讯
2022
收藏  |  浏览/下载:5/0  |  提交时间:2022/03/08
An in vivo screen of noncoding loci reveals that Daedalus is a gatekeeper of an Ikaros-dependent checkpoint during haematopoiesis 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 3
作者:  Harman C.C.D.;  Bailis W.;  Zhao J.;  Hill L.;  Qu R.;  Jackson R.P.;  Shyer J.A.;  Steach H.R.;  Kluger Y.;  Goff L.A.;  Rinn J.L.;  Williams A.;  Henao-Mejia J.;  Flavell R.A.
收藏  |  浏览/下载:38/0  |  提交时间:2021/05/24
Exposure to hypoxia causes stress erythropoiesis and downregulates immune response genes in spleen of mice 期刊论文
BMC GENOMICS, 2021, 卷号: 22, 期号: 1
作者:  Wang, Haijing;  Liu, Daoxin;  Song, Pengfei;  Jiang, Feng;  Chi, Xiangwen;  Zhang, Tongzuo
收藏  |  浏览/下载:38/0  |  提交时间:2022/04/28
EXTRAMEDULLARY HEMATOPOIESIS  TRANSCRIPTION  EXPRESSION  LACKING  PACKAGE  CELLS  POLYCYTHEMIA  RESERVOIR  PROMOTER  KINASE  
Two populations of self-maintaining monocyte-independent macrophages exist in adult epididymis and testis 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 1
作者:  Wang M.;  Yang Y.;  Cansever D.;  Wang Y.;  Kantores C.;  Messiaen S.;  Moison D.;  Livera G.;  Chakarov S.;  Weinberger T.;  Stremmel C.;  Fijak M.;  Klein B.;  Pleuger C.;  Lian Z.;  Ma W.;  Liu Q.;  Klee K.;  Händler K.;  Ulas T.;  Schlitzer A.;  Schultze J.L.;  Becher B.;  Greter M.;  Liu Z.;  Ginhoux F.;  Epelman S.;  Schulz C.;  Meinhardt A.;  Bhushan S.
收藏  |  浏览/下载:31/0  |  提交时间:2021/05/24
Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:  Uckelmann H.J.;  Kim S.M.;  Wong E.M.;  Hatton C.;  Giovinazzo H.;  Gadrey J.Y.;  Krivtsov A.V.;  Rücker F.G.;  Döhner K.;  McGeehan G.M.;  Levine R.L.;  Bullinger L.;  Vassiliou G.S.;  Armstrong S.A.
收藏  |  浏览/下载:25/0  |  提交时间:2020/07/28
antileukemic agent  methionine  unclassified drug  vtp 50469  biological development  cancer  cell  disease treatment  mutation  numerical model  oral health  acute myeloid leukemia  animal cell  animal experiment  animal model  antineoplastic activity  Article  cell proliferation  cell self-renewal  chromatin  controlled study  drug targeting  gene  gene mutation  leukemia cell  molecularly targeted therapy  mouse  mouse model  nonhuman  NPM1 gene  preleukemia  priority journal  Mus  
The evolutionary dynamics and fitness landscape of clonal hematopoiesis 期刊论文
, 2020, 卷号: 367, 期号: 6485
作者:  Watson C.J.;  Papula A.L.;  Poon G.Y.P.;  Wong W.H.;  Young A.L.;  Druley T.E.;  Fisher D.S.;  Blundell J.R.
收藏  |  浏览/下载:21/0  |  提交时间:2020/07/28
DNA methyltransferase 3A  blood  cancer  evolutionary biology  fitness  gene expression  genetic drift  hematology  mutation  pathogenicity  acute myeloid leukemia  age distribution  allele  Article  cancer risk  cell expansion  cell population  clonal hematopoiesis  epigenetics  gene mutation  genetic variability  hematological parameters  hematopoiesis  hematopoietic stem cell  human  molecular evolution  mutational analysis  nonhuman  priority journal  single nucleotide polymorphism  somatic mutation  stem cell self-renewal  
Hope for hematological diseases 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Wilkinson A.C.
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/28
fibronectin  polyvinyl alcohol  serum albumin  stem cell factor  thrombopoietin  blood  disease incidence  disease treatment  laboratory method  medicine  public health  Article  cell differentiation  cell self-renewal  chemotherapy  CRISPR-CAS9 system  ex vivo study  gene editing  gene therapy  genotoxicity  graft versus host reaction  hematologic disease  hematopoiesis  hematopoietic stem cell transplantation  human  morbidity  mortality  multipotent stem cell  nonhuman  priority journal  radiotherapy  stem cell culture  stem cell expansion  
Lineage tracing on transcriptional landscapes links state to fate during differentiation 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  Weinreb C.;  Rodriguez-Fraticelli A.;  Camargo F.D.;  Klein A.M.
收藏  |  浏览/下载:21/0  |  提交时间:2020/07/28
biology  cell component  differentiation  DNA  RNA  transcriptome  algorithm  animal  cell lineage  cytology  DNA barcoding  gene expression  genetics  hematopoiesis  monocyte  mouse  procedures  single cell analysis  Algorithms  Animals  Cell Lineage  DNA Barcoding, Taxonomic  Gene Expression  Hematopoiesis  Mice  Monocytes  RNA-Seq  Single-Cell Analysis  Transcriptome  
Blood transfusion or hematopoiesis? how to select between the subsidy mode and the long-term mode of eco-compensation 期刊论文
Environmental Research Letters, 2020, 卷号: 15, 期号: 9
作者:  Liu M.;  Bai Y.;  Ma N.;  Rao D.;  Yang L.;  Min Q.
收藏  |  浏览/下载:22/0  |  提交时间:2020/12/08
Induction of myelodysplasia by myeloid-derived suppressor cells 期刊论文
JOURNAL OF CLINICAL INVESTIGATION, 2013, 卷号: 123, 期号: 11
作者:  Chen, Xianghong;  Eksioglu, Erika A.;  Zhou, Junmin;  Zhang, Ling;  Djeu, Julie;  Fortenbery, Nicole;  Epling-Burnette, Pearlie;  Van Bijnen, Sandra;  Dolstra, Harry;  Cannon, John;  Youn, Je-in;  Donatelli, Sarah S.;  Qin, Dahui;  De Witte, Theo;  Tao, Jianguo;  Wang, Huaquan;  Cheng, Pingyan;  Gabrilovich, Dmitry I.;  List, Alan;  Wei, Sheng
收藏  |  浏览/下载:17/0  |  提交时间:2021/01/06