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Structure of the RNA-dependent RNA polymerase from COVID-19 virus 期刊论文
, 2020, 卷号: 368, 期号: 6492
作者:  Gao Y.;  Yan L.;  Huang Y.;  Liu F.;  Zhao Y.;  Cao L.;  Wang T.;  Sun Q.;  Ming Z.;  Zhang L.;  Ge J.;  Zheng L.;  Zhang Y.;  Wang H.;  Zhu Y.;  Zhu C.;  Hu T.;  Hua T.;  Zhang B.;  Yang X.;  Li J.;  Yang H.;  Liu Z.;  Xu W.;  Guddat L.W.;  Wang Q.;  Lou Z.;  Rao Z.
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/28
comparative study  drug  electron microscopy  enzyme  enzyme activity  RNA  virus  Coronavirus  SARS coronavirus  adenosine phosphate  alanine  antivirus agent  NSP7 protein, SARS-CoV-2  NSP8 protein, SARS-CoV-2  remdesivir  RNA directed RNA polymerase  RNA-dependent RNA polymerase, coronavirus  viral protein  beta sheet  Betacoronavirus  chemistry  cryoelectron microscopy  drug design  enzyme active site  enzymology  metabolism  molecular model  protein domain  ultrastructure  Adenosine Monophosphate  Alanine  Antiviral Agents  Betacoronavirus  Catalytic Domain  Cryoelectron Microscopy  Drug Design  Models, Molecular  Protein Conformation, beta-Strand  Protein Domains  RNA Replicase  Viral Nonstructural Proteins  
Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Shi J.;  Wen Z.;  Zhong G.;  Yang H.;  Wang C.;  Huang B.;  Liu R.;  He X.;  Shuai L.;  Sun Z.;  Zhao Y.;  Liu P.;  Liang L.;  Cui P.;  Wang J.;  Zhang X.;  Guan Y.;  Tan W.;  Wu G.;  Chen H.;  Bu Z.;  Bu Z.
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/28
bat  canid  disease control  disease transmission  felid  global perspective  infectious disease  poultry  severe acute respiratory syndrome  viral disease  virus  China  Hubei  Wuhan  Anas  Animalia  Canis familiaris  Coronavirus  Gallus gallus  Mustela  SARS coronavirus  Suidae  virus antibody  virus RNA  animal  Betacoronavirus  blood  cat  chicken  Coronavirus infection  disease model  disease predisposition  dog  domestic animal  duck  feces  female  immunology  isolation and purification  male  Mustela putorius furo  pandemic  physiology  pig  respiratory system  species difference  virology  virus attachment  virus pneumonia  virus replication  Animals  Animals, Domestic  Antibodies, Viral  Betacoronavirus  Cats  Chickens  Coronavirus Infections  Disease Models, Animal  Disease Susceptibility  Dogs  Ducks  Feces  Female  Ferrets  Male  Pandemics  Pneumonia, Viral  Respiratory System  RNA, Viral  Species Specificity  Sus scrofa  Virus Attachment  Virus Replication  
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance 期刊论文
, 2020, 卷号: 367, 期号: 6475
作者:  ElTanbouly M.A.;  Zhao Y.;  Nowak E.;  Li J.;  Schaafsma E.;  Le Mercier I.;  Ceeraz S.;  Lines J.L.;  Peng C.;  Carriere C.;  Huang X.;  Day M.;  Koehn B.;  Lee S.W.;  Morales M.S.;  Hogquist K.A.;  Jameson S.C.;  Mueller D.;  Rothstein J.;  Blazar B.R.;  Cheng C.;  Noelle R.J.
收藏  |  浏览/下载：46/0  |  提交时间：2020/07/28
cell protein  interferon  kruppel like factor 2  T lymphocyte receptor  unclassified drug  V type immunoglobulin domain containing suppressor of T cell activation protein  B7 antigen  Dies1 protein, mouse  lymphocyte antigen receptor  membrane protein  monoclonal antibody  VSIR protein, human  biological development  cell  gene expression  heterogeneity  homeostasis  immune response  immunity  tolerance  acute graft versus host disease  animal cell  animal experiment  animal model  Article  CD4+ T lymphocyte  cell death  cell expansion  cell fate  cell heterogeneity  cell loss  cell survival  controlled study  female  gene  gene deletion  homeostasis  immunological tolerance  in vivo study  long term survival  male  mouse  nonhuman  phenotype  priority journal  protein expression  protein function  rheumatoid arthritis  RNA sequencing  systemic lupus erythematosus  T lymphocyte  T lymphocyte activation  T lymphocyte subpopulation  TCR gene  upregulation  VISTA gene  animal  C57BL mouse  genetics  immunological tolerance  immunology  knockout mouse  lymphocyte activation  physiology  T lymphocyte  Mus  Animals  Antibodies, Monoclonal  B7 Antigens  Lymphocyte Activation  Membrane Proteins  Mice  Mice, Inbred C57BL  Mice, Knockout  Peripheral Tolerance  Receptors, Antigen, T-Cell  T-Lymphocytes