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Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking 期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:  Lepack A.E.;  Werner C.T.;  Stewart A.F.;  Fulton S.L.;  Zhong P.;  Farrelly L.A.;  Smith A.C.W.;  Ramakrishnan A.;  Lyu Y.;  Bastle R.M.;  Martin J.A.;  Mitra S.;  O'Connor R.M.;  Wang Z.-J.;  Molina H.;  Turecki G.;  Shen L.;  Yan Z.;  Calipari E.S.;  Dietz D.M.;  Kenny P.J.;  Maze I.
收藏  |  浏览/下载：37/0  |  提交时间：2020/07/28
amidase  dopamine  histone H3  histone transamidase  protein glutamine gamma glutamyltransferase 2  RNA  unclassified drug  brain  cell  chemical compound  chemical reaction  gene expression  genetic analysis  protein  action potential  amino acid substitution  amino terminal sequence  Article  cocaine dependence  controlled study  dopamine release  dopaminergic nerve cell  dopaminergic transmission  down regulation  drug seeking behavior  enzyme activity  gene expression  histone dopaminylation  histone modification  human  human tissue  hyperpolarization  in vitro study  motivation  nerve cell plasticity  nerve projection  neuropathology  nucleus accumbens  priority journal  protein expression  protein function  reward  RNA sequence  ventral tegmentum  Rattus  
Genetics of schizophrenia in the South African Xhosa 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:  Gulsuner S.;  Stein D.J.;  Susser E.S.;  Sibeko G.;  Pretorius A.;  Walsh T.;  Majara L.;  Mndini M.M.;  Mqulwana S.G.;  Ntola O.A.;  Casadei S.;  Ngqengelele L.L.;  Korchina V.;  Van Der Merwe C.;  Malan M.;  Fader K.M.;  Feng M.;  Willoughby E.;  Muzny D.;  Baldinger A.;  Andrews H.F.;  Gur R.C.;  Gibbs R.A.;  Zingela Z.;  Nagdee M.;  Ramesar R.S.;  King M.-C.;  McClellan J.M.
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/28
4 aminobutyric acid  dopamine  glutamine  genetic analysis  genetic variation  genome  genomics  mutagenicity  mutation  Article  connectome  controlled study  gene mutation  genetic variability  genetics  human  major clinical study  nerve cell plasticity  priority journal  schizophrenia  South African  Xhosa (people)  South Africa  
Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila 期刊论文
, 2020, 卷号: 367, 期号: 6483
作者:  Hervas R.;  Rau M.J.;  Park Y.;  Zhang W.;  Murzin A.G.;  Fitzpatrick J.A.J.;  Scheres S.H.W.;  Si K.
收藏  |  浏览/下载：23/0  |  提交时间：2020/07/28
amyloid protein  cytoplasmic polyadenylation element binding protein  insect protein  protein Orb2  unclassified drug  adult  memory  neurology  protein  substrate  turnover  Article  cryoelectron microscopy  Drosophila  enzyme activity  hydrophilicity  hydrophobicity  memory  nerve cell  nonhuman  priority journal  protein aggregation  protein function  protein isolation  protein processing  protein structure  
Structural basis of second-generation HIV integrase inhibitor action and viral resistance 期刊论文
, 2020, 卷号: 367, 期号: 6479
作者:  Cook N.J.;  Li W.;  Berta D.;  Badaoui M.;  Ballandras-Colas A.;  Nans A.;  Kotecha A.;  Rosta E.;  Engelman A.N.;  Cherepanov P.
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/28
bictegravir  dolutegravir  lens epithelium derived growth factor  magnesium ion  bictegravir  dolutegravir  fused heterocyclic rings  glutamine  glycine  histidine  integrase  integrase inhibitor  magnesium  serine  acquired immune deficiency syndrome  amino acid  drug  human immunodeficiency virus  inhibitor  protein  ultrastructure  virus  amino acid substitution  amino terminal sequence  Article  carboxy terminal sequence  cryoelectron microscopy  DNA binding  drug design  drug protein binding  drug structure  enzyme active site  gene mutation  Human immunodeficiency virus 1  in vitro study  molecular dynamics  molecular stability  nonhuman  pharmacophore  polarization  priority journal  protonation  virus resistance  antiviral resistance  chemistry  genetics  human  mutation  procedures  single molecule imaging  Amino Acid Substitution  Catalytic Domain  Cryoelectron Microscopy  Drug Resistance, Viral  Glutamine  Glycine  Heterocyclic Compounds, 3-Ring  Heterocyclic Compounds, 4 or More Rings  Histidine  HIV Integrase  HIV Integrase Inhibitors  Humans  Magnesium  Mutation  Serine  Single Molecule Imaging  
Global control of bacterial nitrogen and carbon metabolism by a PTSNtr-regulated switch 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2020, 卷号: 117, 期号: 19
作者:  Sánchez-Cañizares C.;  Prell J.;  Pini F.;  Rutten P.;  Kraxner K.;  Wynands B.;  Karunakaran R.;  Poole P.S.
收藏  |  浏览/下载：21/0  |  提交时间：2021/01/06