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DOI | 10.1016/j.envint.2016.06.010 |
Coupled near-field and far-field exposure assessment framework for chemicals in consumer products | |
Fantke, Peter1; Ernstoff, Alexi S.1; Huang, Lei2; Csiszar, Susan A.3; Jolliet, Olivier2 | |
发表日期 | 2016-09-01 |
ISSN | 0160-4120 |
卷号 | 94页码:508-518 |
英文摘要 | Humans can be exposed to chemicals in consumer products through product use and environmental emissions over the product life cycle. Exposure pathways are often complex, where chemicals can transfer directly from products to humans during use or exchange between various indoor and outdoor compartments until sub-fractions reach humans. To consistently evaluate exposure pathways along product life cycles, a flexible mass balance-based assessment framework is presented structuring multimedia chemical transfers in a matrix of direct inter-compartmental transfer fractions. By matrix inversion, we quantify cumulative multimedia transfer fractions and exposure pathway-specific product intake fractions defined as chemical mass taken in by humans per unit mass of chemical in a product. Combining product intake fractions with chemical mass in the product yields intake estimates for use in life cycle impact assessment and chemical alternatives assessment, or daily intake doses for use in risk-based assessment and high-throughput screening. Two illustrative examples of chemicals used in personal care products and flooring materials demonstrate how this matrix-based framework offers a consistent and efficient way to rapidly compare exposure pathways for adult and child users and for the general population. This framework constitutes a user-friendly approach to develop, compare and interpret multiple human exposure scenarios in a coupled system of near-field ('user' environment), far-field and human intake compartments, and helps understand the contribution of individual pathways to overall human exposure in various product application contexts to inform decisions in different science-policy fields for which exposure quantification is relevant (C) 2016 The Authors. Published by Elsevier Ltd. |
英文关键词 | Near-field consumer exposure;Multimedia multi-pathway framework;Product intake fraction;Life cycle impact assessment;Chemical alternatives assessment;High-throughput risk screening |
语种 | 英语 |
WOS记录号 | WOS:000382339000056 |
来源期刊 | ENVIRONMENT INTERNATIONAL
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来源机构 | 美国环保署 |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/60704 |
作者单位 | 1.Tech Univ Denmark, Dept Engn Management, Quantitat Sustainabil Assessment Div, Prod Storvet 424, DK-2800 Lyngby, Denmark; 2.Univ Michigan, Environm Hlth Sci, 1415 Washington Hts, Ann Arbor, MI 48109 USA; 3.US EPA, Oak Ridge Inst Sci & Educ, Ncit Risk Management Res Lab, Cincinnati, OH 45268 USA |
推荐引用方式 GB/T 7714 | Fantke, Peter,Ernstoff, Alexi S.,Huang, Lei,et al. Coupled near-field and far-field exposure assessment framework for chemicals in consumer products[J]. 美国环保署,2016,94:508-518. |
APA | Fantke, Peter,Ernstoff, Alexi S.,Huang, Lei,Csiszar, Susan A.,&Jolliet, Olivier.(2016).Coupled near-field and far-field exposure assessment framework for chemicals in consumer products.ENVIRONMENT INTERNATIONAL,94,508-518. |
MLA | Fantke, Peter,et al."Coupled near-field and far-field exposure assessment framework for chemicals in consumer products".ENVIRONMENT INTERNATIONAL 94(2016):508-518. |
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