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DOI | 10.1016/j.envint.2016.11.017 |
Probabilistic approach for assessing infants' health risks due to ingestion of nanoscale silver released from consumer products | |
Pang, Chengfang1; Hristozov, Danail1,2; Zabeo, Alex1,2; Pizzol, Lisa1,2; Tsang, Michael P.3,4; Sayre, Phil5; Marcomini, Antonio1 | |
发表日期 | 2017-02-01 |
ISSN | 0160-4120 |
卷号 | 99页码:199-207 |
英文摘要 | Silver nanoparticles (n-Ag) are widely used in consumer products and many medical applications because of their unique antibacterial properties. Their use is raising concern about potential human exposures and health effects. Therefore, it is informative to assess the potential human health risks of n-Ag in order to ensure that nano technology-based consumer products are deployed in a safe and sustainable way. Even though toxicity studies clearly show the potential hazard of n-Ag, there have been few attempts to integrate hazard and exposure assessments to evaluate risks. The underlying reason for this is the difficulty in characterizing exposure and the lack of toxicity studies essential for human health risk assessment (HHRA). Such data gaps introduce significant uncertainty into the risk assessment process. This study uses probabilistic methods to assess the relative uncertainty and potential risks of n-Ag exposure to infants. In this paper, we estimate the risks for infants potentially exposed to n-Ag through drinking juice or milk from sippy cups or licking baby blankets containing n-Ag. We explicitly evaluate uncertainty and variability contained in available dose-response and exposure data in order to make the risk characterization process transparent. Our results showed that individual margin of exposures for oral exposure to sippy cups and baby blankets containing n-Ag exhibited minimal risk. (C) 2016 Published by Elsevier Ltd. |
英文关键词 | Silver nanoparticles;Human health risk assessment;Engineered nanomaterials;Stochastic risk assessment |
语种 | 英语 |
WOS记录号 | WOS:000394062700018 |
来源期刊 | ENVIRONMENT INTERNATIONAL
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来源机构 | 美国环保署 |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/60519 |
作者单位 | 1.Ca Foscari Univ Venice, Dept Environm Sci Informat & Stat, Via Torino 155, I-30172 Venice, VE, Italy; 2.Green Decis Srl, Genoa, Italy; 3.Univ Bordeaux, ISM, UMR 5255, F-33400 Talence, France; 4.Univ Bordeaux, CNRS, ISM, UMR 5255, F-33400 Talence, France; 5.US EPA, Washington, DC 20460 USA |
推荐引用方式 GB/T 7714 | Pang, Chengfang,Hristozov, Danail,Zabeo, Alex,et al. Probabilistic approach for assessing infants' health risks due to ingestion of nanoscale silver released from consumer products[J]. 美国环保署,2017,99:199-207. |
APA | Pang, Chengfang.,Hristozov, Danail.,Zabeo, Alex.,Pizzol, Lisa.,Tsang, Michael P..,...&Marcomini, Antonio.(2017).Probabilistic approach for assessing infants' health risks due to ingestion of nanoscale silver released from consumer products.ENVIRONMENT INTERNATIONAL,99,199-207. |
MLA | Pang, Chengfang,et al."Probabilistic approach for assessing infants' health risks due to ingestion of nanoscale silver released from consumer products".ENVIRONMENT INTERNATIONAL 99(2017):199-207. |
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