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DOI | 10.1038/jes.2017.29 |
Consumer product chemical weight fractions from ingredient lists | |
Isaacs, Kristin K.1; Phillips, Katherine A.1; Biryol, Derya1,2; Dionisio, Kathie L.1; Price, Paul S.1 | |
发表日期 | 2018-05-01 |
ISSN | 1559-0631 |
卷号 | 28期号:3页码:216-222 |
英文摘要 | Assessing human exposures to chemicals in consumer products requires composition information. However, comprehensive composition data for products in commerce are not generally available. Many consumer products have reported ingredient lists that are constructed using specific guidelines. A probabilistic model was developed to estimate quantitative weight fraction (WF) values that are consistent with the rank of an ingredient in the list, the number of reported ingredients, and labeling rules. The model provides the mean, median, and 95% upper and lower confidence limit WFs for ingredients of any rank in lists of any length. WFs predicted by the model compared favorably with those reported on Material Safety Data Sheets. Predictions for chemicals known to provide specific functions in products were also found to reasonably agree with reported WFs. The model was applied to a selection of publicly available ingredient lists, thereby estimating WFs for 1293 unique ingredients in 1123 products in 81 product categories. Predicted WFs, although less precise than reported values, can be estimated for large numbers of product-chemical combinations and thus provide a useful source of data for high-throughput or screening-level exposure assessments. |
英文关键词 | consumer products;consumer exposures;ExpoCast;ingredients |
语种 | 英语 |
WOS记录号 | WOS:000430457100002 |
来源期刊 | JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
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来源机构 | 美国环保署 |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/58590 |
作者单位 | 1.US EPA, Off Res & Dev, Natl Exposure Res Lab, E205-02,109 TW Alexander Dr, Res Triangle Pk, NC 27709 USA; 2.Oak Ridge Inst Sci & Educ, Oak Ridge, TN 37830 USA |
推荐引用方式 GB/T 7714 | Isaacs, Kristin K.,Phillips, Katherine A.,Biryol, Derya,et al. Consumer product chemical weight fractions from ingredient lists[J]. 美国环保署,2018,28(3):216-222. |
APA | Isaacs, Kristin K.,Phillips, Katherine A.,Biryol, Derya,Dionisio, Kathie L.,&Price, Paul S..(2018).Consumer product chemical weight fractions from ingredient lists.JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY,28(3),216-222. |
MLA | Isaacs, Kristin K.,et al."Consumer product chemical weight fractions from ingredient lists".JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY 28.3(2018):216-222. |
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