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DOI | 10.1016/j.envint.2014.07.009 |
Effect modification of ozone-related mortality risks by temperature in 97 US cities | |
Jhun, Iny1; Fann, Neal2; Zanobetti, Antonella1; Hubbell, Bryan2 | |
发表日期 | 2014-12-01 |
ISSN | 0160-4120 |
卷号 | 73页码:128-134 |
英文摘要 | Many time-series studies have characterized the relationship between short-term ozone exposure and adverse health outcomes, controlling for temperature as a confounder. Temperature may also modify ozone effects, though this has been largely under-investigated. In this study, we explored whether temperature modifies the effect of short-term ozone exposure on mortality. We used the database developed for the National Morbidity and Mortality Air Pollution Study to estimate ozone mortality risks in 97 US cities in May through September, 1987-2000. We treated temperature as a confounder as well as an effect modifier by estimating risks at low, moderate, and high temperature categories. When temperature was treated as a confounder, a 10-ppb increase in daily 24-h ozone was associated with a 0.47% (95% CI: 0.19%-0.76%) increase in mortality. When we assessed effect modification by temperature, the interaction between ozone and temperature was not statistically significant However, there was a U-shaped pattern in mortality risk, which was greater at the low (<25th percentile) and high (>75th percentile) temperature levels than moderate temperature levels. At the high temperature category, a 10% increase in AC prevalence mitigated mortality risk associated with 10-ppb of ozone exposure by -0.18% (95% CI: -0.35%, -0.02%). Furthermore, ozone mortality risk in the high temperature category increased as we restricted our analyses to hotter days. On days where temperatures exceeded the 75th, 90th, and 95th percentile temperatures, a 10-ppb increase in ozone was associated with a 0.65% (95% CI: 0.20%-1.09%), 0.83% (95% CI: 0.17%-1.48%), and 135% (95% CI: 0.44%-2.27%) increase in mortality, respectively. These results suggested that high temperatures may exacerbate physiological responses to short-term ozone exposure. (C) 2014 Elsevier Ltd. All rights reserved. |
英文关键词 | Ozone;Temperature;Mortality;Effect modification;Air conditioning |
语种 | 英语 |
WOS记录号 | WOS:000345540700015 |
来源期刊 | ENVIRONMENT INTERNATIONAL |
来源机构 | 美国环保署 |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/57345 |
作者单位 | 1.Harvard Univ, Sch Publ Hlth, Dept Environm Hlth, Boston, MA 02115 USA; 2.US EPA, Off Air Qual Planning & Stand, Res Triangle Pk, NC 27711 USA |
推荐引用方式 GB/T 7714 | Jhun, Iny,Fann, Neal,Zanobetti, Antonella,et al. Effect modification of ozone-related mortality risks by temperature in 97 US cities[J]. 美国环保署,2014,73:128-134. |
APA | Jhun, Iny,Fann, Neal,Zanobetti, Antonella,&Hubbell, Bryan.(2014).Effect modification of ozone-related mortality risks by temperature in 97 US cities.ENVIRONMENT INTERNATIONAL,73,128-134. |
MLA | Jhun, Iny,et al."Effect modification of ozone-related mortality risks by temperature in 97 US cities".ENVIRONMENT INTERNATIONAL 73(2014):128-134. |
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