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DOI | 10.1021/acs.est.6b02277 |
Conceptual Framework To Extend Life Cycle Assessment Using Near Field Human Exposure Modeling and High-Throughput Tools for Chemicals | |
Csiszar, Susan A.1; Meyer, David E.2; Dionisio, Kathie L.3; Egeghy, Peter3; Isaacs, Kristin K.3; Price, Paul S.3; Scanlon, Kelly A.4; Tan, Yu-Mei3; Thomas, Kent3; Vallero, Daniel3; Bare, Jane C.2 | |
发表日期 | 2016-11-01 |
ISSN | 0013-936X |
卷号 | 50期号:21页码:11922-11934 |
英文摘要 | Life Cycle Assessment (LCA) is a decision-making tool that accounts for multiple impacts across the life cycle of a product or service. This paper presents a conceptual framework to integrate human health impact assessment with risk screening approaches to extend LCA to include near-field chemical sources (e.g., those originating from consumer products and building materials) that have traditionally been excluded from LCA. A new generation of rapid human exposure modeling and high-throughput toxicity testing is transforming chemical risk prioritization and provides an opportunity for integration of screening-level risk assessment (RA) with LCA. The combined LCA and RA approach considers environmental impacts of products alongside risks to human health, which is consistent with regulatory frameworks addressing RA within a sustainability mindset. A case study is presented to juxtapose LCA and risk screening approaches for a chemical used in a consumer product. The case study demonstrates how these new risk screening tools can be used to inform toxicity impact estimates in LCA and highlights needs for future research. The framework provides a basis for developing tools and methods to support decision making on the use of chemicals in products. |
语种 | 英语 |
WOS记录号 | WOS:000386991100056 |
来源期刊 | ENVIRONMENTAL SCIENCE & TECHNOLOGY
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来源机构 | 美国环保署 |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/57274 |
作者单位 | 1.US EPA, Oak Ridge Inst Sci & Educ ORISE, Res Participat Program, 26 West Martin Luther King Dr, Cincinnati, OH 45268 USA; 2.US EPA, Off Res & Dev, Natl Risk Management Res Lab, 26 West Martin Luther King Dr, Cincinnati, OH 45268 USA; 3.US EPA, Off Res & Dev, Natl Exposure Res Lab, Res Triangle Pk, NC 27711 USA; 4.US EPA, Off Air & Radiat, Off Radiat & Indoor Air, Washington, DC 20460 USA |
推荐引用方式 GB/T 7714 | Csiszar, Susan A.,Meyer, David E.,Dionisio, Kathie L.,et al. Conceptual Framework To Extend Life Cycle Assessment Using Near Field Human Exposure Modeling and High-Throughput Tools for Chemicals[J]. 美国环保署,2016,50(21):11922-11934. |
APA | Csiszar, Susan A..,Meyer, David E..,Dionisio, Kathie L..,Egeghy, Peter.,Isaacs, Kristin K..,...&Bare, Jane C..(2016).Conceptual Framework To Extend Life Cycle Assessment Using Near Field Human Exposure Modeling and High-Throughput Tools for Chemicals.ENVIRONMENTAL SCIENCE & TECHNOLOGY,50(21),11922-11934. |
MLA | Csiszar, Susan A.,et al."Conceptual Framework To Extend Life Cycle Assessment Using Near Field Human Exposure Modeling and High-Throughput Tools for Chemicals".ENVIRONMENTAL SCIENCE & TECHNOLOGY 50.21(2016):11922-11934. |
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