气候变化领域集成服务门户(CCPortal): Effects of meteorological factors on influenza transmissibility by virus type/subtype

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DOI	10.1186/s12889-024-17961-9
	Effects of meteorological factors on influenza transmissibility by virus type/subtype
	Yan, Ze-Lin; Liu, Wen-Hui; Long, Yu-Xiang; Ming, Bo-Wen; Yang, Zhou; Qin, Peng-Zhe; Ou, Chun-Quan; Li, Li
发表日期	2024
EISSN	1471-2458
起始页码	24
结束页码	1
卷号	24 期号:1
英文摘要	Background Quantitative evidence on the impact of meteorological factors on influenza transmissibility across different virus types/subtypes is scarce, and no previous studies have reported the effect of hourly temperature variability (HTV) on influenza transmissibility. Herein, we explored the associations between meteorological factors and influenza transmissibility according to the influenza type and subtype in Guangzhou, a subtropical city in China. Methods We collected influenza surveillance and meteorological data of Guangzhou between October 2010 and December 2019. Influenza transmissibility was measured using the instantaneous effective reproductive number (R-t). A gamma regression with a log link combined with a distributed lag non-linear model was used to assess the associations of daily meteorological factors with R-t by influenza types/subtypes. Results The exposure-response relationship between ambient temperature and R-t was non-linear, with elevated transmissibility at low and high temperatures. Influenza transmissibility increased as HTV increased when HTV < around 4.5 degrees C. A non-linear association was observed between absolute humidity and R-t, with increased transmissibility at low absolute humidity and at around 19 g/m(3). Relative humidity had a U-shaped association with influenza transmissibility. The associations between meteorological factors and influenza transmissibility varied according to the influenza type and subtype: elevated transmissibility was observed at high ambient temperatures for influenza A(H3N2), but not for influenza A(H1N1)pdm09; transmissibility of influenza A(H1N1)pdm09 increased as HTV increased when HTV < around 4.5 degrees C, but the transmissibility decreased with HTV when HTV < 2.5 degrees C and 3.0 degrees C for influenza A(H3N2) and B, respectively; positive association of R-t with absolute humidity was witnessed for influenza A(H3N2) even when absolute humidity was larger than 19 g/m(3), which was different from that for influenza A(H1N1)pdm09 and influenza B. Conclusions Temperature variability has an impact on influenza transmissibility. Ambient temperature, temperature variability, and humidity influence the transmissibility of different influenza types/subtypes discrepantly. Our findings have important implications for improving preparedness for influenza epidemics, especially under climate change conditions.
英文关键词	Meteorological factors; Hourly temperature variability; Influenza; Instantaneous effective reproductive number; Distributed lag non-linear model
语种	英语
WOS研究方向	Public, Environmental & Occupational Health
WOS类目	Public, Environmental & Occupational Health
WOS记录号	WOS:001163711300015
来源期刊	BMC PUBLIC HEALTH
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/305067
作者单位	Southern Medical University - China
推荐引用方式 GB/T 7714	Yan, Ze-Lin,Liu, Wen-Hui,Long, Yu-Xiang,et al. Effects of meteorological factors on influenza transmissibility by virus type/subtype[J],2024,24(1).
APA	Yan, Ze-Lin.,Liu, Wen-Hui.,Long, Yu-Xiang.,Ming, Bo-Wen.,Yang, Zhou.,...&Li, Li.(2024).Effects of meteorological factors on influenza transmissibility by virus type/subtype.BMC PUBLIC HEALTH,24(1).
MLA	Yan, Ze-Lin,et al."Effects of meteorological factors on influenza transmissibility by virus type/subtype".BMC PUBLIC HEALTH 24.1(2024).