气候变化领域集成服务门户(CCPortal): Regulation of body temperature and blood pressure in women: Mechanisms and implications for heat illness risk

CCPortal

DOI	10.1113/EP091455
	Regulation of body temperature and blood pressure in women: Mechanisms and implications for heat illness risk
	Giersch, Gabrielle E. W.; Charkoudian, Nisha
发表日期	2024
ISSN	0958-0670
EISSN	1469-445X
英文摘要	Increasing global temperatures due to ongoing climate change phenomena have resulted in increased risk of exertional heat illness in otherwise healthy, young individuals who work or play in the heat. With increasing participation of women in athletic, military and industrial activities that involve exertion in the heat, there is a growing need to study female physiology in this context. Mechanisms controlling blood pressure and body temperature have substantial overlap in humans, largely due to autonomic mechanisms which contribute to both. Similarly, illnesses that result from excessive heat exposure can often be traced back to imbalances in one or more of these autonomic mechanisms. In recent years, there has been increased recognition of the importance of sex as a biological variable for basic and applied research in these areas. The goal of this paper is to present an update on the integrative physiology and pathophysiology of responses to heat stress in women (thermoregulation and blood pressure regulation). In this context, it is often the case that differences between sexes are presented as 'advantages' and 'disadvantages' of one sex over the other. In our opinion, this is an over-simplification of the physiology which ignores the nuances and complexities of the integrative physiology of responses to heat exposure and exercise, and their relevance for practical outcomes. What is the topic of this review? Integrative mechanisms of body temperature and blood pressure regulation in women. What advances does it highlight? A framework is provided for conceptualizing the integrative nature of blood pressure regulation and thermoregulation in women as dynamic and circumstance-specific. In almost all situations, any 'advantage' for one sex could also be a 'disadvantage' if conditions were altered.
英文关键词	exercise; exertional heat stroke; integrative physiology; sex differences; thermoregulation
语种	英语
WOS研究方向	Physiology
WOS类目	Physiology
WOS记录号	WOS:001200659700001
来源期刊	EXPERIMENTAL PHYSIOLOGY
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/300895
作者单位	United States Department of Defense; United States Army; United States Department of Defense; United States Army
推荐引用方式 GB/T 7714	Giersch, Gabrielle E. W.,Charkoudian, Nisha. Regulation of body temperature and blood pressure in women: Mechanisms and implications for heat illness risk[J],2024.
APA	Giersch, Gabrielle E. W.,&Charkoudian, Nisha.(2024).Regulation of body temperature and blood pressure in women: Mechanisms and implications for heat illness risk.EXPERIMENTAL PHYSIOLOGY.
MLA	Giersch, Gabrielle E. W.,et al."Regulation of body temperature and blood pressure in women: Mechanisms and implications for heat illness risk".EXPERIMENTAL PHYSIOLOGY (2024).