气候变化领域集成服务门户(CCPortal): Climate warming, environmental degradation and pollution as drivers of antibiotic resistance

CCPortal

DOI	10.1016/j.envpol.2024.123649
	Climate warming, environmental degradation and pollution as drivers of antibiotic resistance
	Rzymski, Piotr; Gwenzi, Willis; Poniedzialek, Barbara; Mangul, Serghei; Fal, Andrzej
发表日期	2024
ISSN	0269-7491
EISSN	1873-6424
起始页码	346
卷号	346
英文摘要	Antibiotic resistance is a major challenge to public health, but human-caused environmental changes have not been widely recognized as its drivers. Here, we provide a comprehensive overview of the relationships between environmental degradation and antibiotic resistance, demonstrating that the former can potentially fuel the latter with significant public health outcomes. We describe that (i) global warming favors horizontal gene transfer, bacterial infections, the spread of drug-resistant pathogens due to water scarcity, and the release of resistance genes with wastewater; (ii) pesticide and metal pollution act as co-selectors of antibiotic resistance mechanisms; (iii) microplastics create conditions promoting and spreading antibiotic resistance and resistant bacteria; (iv) changes in land use, deforestation, and environmental pollution reduce microbial diversity, a natural barrier to antibiotic resistance spread. We argue that management of antibiotic resistance must integrate environmental goals, including mitigation of further increases in the Earth's surface temperature, better qualitative and quantitative protection of water resources, strengthening of sewage infrastructure and improving wastewater treatment, counteracting the microbial diversity loss, reduction of pesticide and metal emissions, and plastic use, and improving waste recycling. These actions should be accompanied by restricting antibiotic use only to clinically justified situations, developing novel treatments, and promoting prophylaxis. It is pivotal for health authorities and the medical community to adopt the protection of environmental quality as a part of public health measures, also in the context of antibiotic resistance management.
英文关键词	Antibiotic resistance; Climate change; Microplastic; Biodiversity; Pesticides; Toxic metals
语种	英语
WOS研究方向	Environmental Sciences & Ecology
WOS类目	Environmental Sciences
WOS记录号	WOS:001202447900001
来源期刊	ENVIRONMENTAL POLLUTION
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/298645
作者单位	Poznan University of Medical Sciences; Universitat Kassel; Leibniz Institut fur Agrartechnik und Biookonomie (ATB); University of Southern California; Cardinal Stefan Wyszynski University in Warsaw; Poznan University of Medical Sciences
推荐引用方式 GB/T 7714	Rzymski, Piotr,Gwenzi, Willis,Poniedzialek, Barbara,et al. Climate warming, environmental degradation and pollution as drivers of antibiotic resistance[J],2024,346.
APA	Rzymski, Piotr,Gwenzi, Willis,Poniedzialek, Barbara,Mangul, Serghei,&Fal, Andrzej.(2024).Climate warming, environmental degradation and pollution as drivers of antibiotic resistance.ENVIRONMENTAL POLLUTION,346.
MLA	Rzymski, Piotr,et al."Climate warming, environmental degradation and pollution as drivers of antibiotic resistance".ENVIRONMENTAL POLLUTION 346(2024).