气候变化领域集成服务门户(CCPortal): Integrating genomics into the genetic management of the endangered mountain yellow-legged frog

CCPortal

DOI	10.1007/s10592-023-01594-3
	Integrating genomics into the genetic management of the endangered mountain yellow-legged frog
	Steiner, Cynthia C.; Jacobs, Leah; Choi, Emma; Ivy, Jamie; Wilder, Aryn; Calatayud, Natalie E.; Shier, Debra M.
发表日期	2024
ISSN	1566-0621
EISSN	1572-9737
英文摘要	Conservation breeding programs have long been an important management tool for species recovery. Recently, breeding programs have begun to integrate next generation sequencing data into pedigree-based management strategies designed to maximize retention of genetic diversity and minimize inbreeding. In 2005, an ex situ breeding program for two of the three extant, geographically separate populations of the endangered southern mountain yellow-legged frog (Rana muscosa) was established at the San Diego Zoo Wildlife Alliance. To provide improved breeding recommendations for the species, we conducted molecular population genetic assessments using double digest restriction site-associated DNA sequencing data. We first studied genetic diversity, population differentiation, and genetic structure of wild frogs to validate the status of management units in R. muscosa. Genetic diversity was relatively low (HO = 0.166-0.245), population differentiation moderate (FST = 0.29), and patterns of genetic structure and admixture supported the evolutionary divergence of frogs by mountain ranges with limited gene flow. In the breeding program, relatedness estimates identified close relatives amongst the founders, and molecularly-derived kinship values were used to determine and rank suitable breeders to minimize population mean kinship. Ex situ management recommendations highlight the need for importing additional founders from the wild to enhance genetic diversity in the breeding program, as an effective source for genetic restoration. Alternatively, the use of advanced reproductive technologies to capture wild diversity without removal of individuals from the wild seem promising.
英文关键词	Amphibian; Breeding program; Management; Conservation genetics; RADseq
语种	英语
WOS研究方向	Biodiversity & Conservation ; Genetics & Heredity
WOS类目	Biodiversity Conservation ; Genetics & Heredity
WOS记录号	WOS:001137587000001
来源期刊	CONSERVATION GENETICS
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/297778
作者单位	University of Connecticut
推荐引用方式 GB/T 7714	Steiner, Cynthia C.,Jacobs, Leah,Choi, Emma,et al. Integrating genomics into the genetic management of the endangered mountain yellow-legged frog[J],2024.
APA	Steiner, Cynthia C..,Jacobs, Leah.,Choi, Emma.,Ivy, Jamie.,Wilder, Aryn.,...&Shier, Debra M..(2024).Integrating genomics into the genetic management of the endangered mountain yellow-legged frog.CONSERVATION GENETICS.
MLA	Steiner, Cynthia C.,et al."Integrating genomics into the genetic management of the endangered mountain yellow-legged frog".CONSERVATION GENETICS (2024).