气候变化领域集成服务门户(CCPortal): Amazon Biobank: Assessing the Implementation of a Blockchain-Based Genomic Database

CCPortal

DOI	10.1109/ACCESS.2024.3354716
	Amazon Biobank: Assessing the Implementation of a Blockchain-Based Genomic Database
	Kimura, Leonardo T.; Shiraishi, Felipe K.; Andrade, Ewerton R.; Carvalho, Tereza C. M. B.; Simplicio Jr, Marcos A.
发表日期	2024
ISSN	2169-3536
起始页码	12
卷号	12
英文摘要	The bioeconomy, an industrial production model based on biological resources and sustainable development, can be considered an emerging opportunity for biodiversity-abundant regions, such as the Amazon rainforest. However, existing genomic repositories lack data traceability and economic benefit-sharing mechanisms, resulting in limited motivation for data providers to contribute. To address this challenge, we present an implementation of Amazon Biobank, a community-driven genetic database. By leveraging blockchain and peer-to-peer (P2P) technologies, we enable distributed and transparent data sharing; meanwhile, by using smart contracts directly registered in the system, we enforce fair benefit-sharing among all system participants. Moreover, Amazon Biobank is designed to be auditable by any user, reducing the need for trusted system managers. This paper aims to validate this model, by describing the implementation of a prototype using Hyperledger Fabric and BitTorrent and evaluating its performance. Our results show that the prototype can support at least 400 transactions per second in a small network, a number that can be further improved by adding new nodes or allocating additional computational resources. We conclude that the Amazon Biobank proposal is technically feasible, and its real-world deployment has the potential to foster sustainable development in high-biodiversity regions, in addition to promoting collaborative biotechnology research.
英文关键词	Blockchains; Peer-to-peer computing; Bioinformatics; Genomics; Collaboration; Consensus protocol; Bitcoin; Biodiversity; Sustainable development; blockchains; genomic database; sustainable development; peer-to-peer computing
语种	英语
WOS研究方向	Computer Science ; Engineering ; Telecommunications
WOS类目	Computer Science, Information Systems ; Engineering, Electrical & Electronic ; Telecommunications
WOS记录号	WOS:001150378500001
来源期刊	IEEE ACCESS
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/296141
作者单位	Universidade de Sao Paulo; Universidade Federal de Rondonia
推荐引用方式 GB/T 7714	Kimura, Leonardo T.,Shiraishi, Felipe K.,Andrade, Ewerton R.,et al. Amazon Biobank: Assessing the Implementation of a Blockchain-Based Genomic Database[J],2024,12.
APA	Kimura, Leonardo T.,Shiraishi, Felipe K.,Andrade, Ewerton R.,Carvalho, Tereza C. M. B.,&Simplicio Jr, Marcos A..(2024).Amazon Biobank: Assessing the Implementation of a Blockchain-Based Genomic Database.IEEE ACCESS,12.
MLA	Kimura, Leonardo T.,et al."Amazon Biobank: Assessing the Implementation of a Blockchain-Based Genomic Database".IEEE ACCESS 12(2024).