气候变化领域集成服务门户(CCPortal): Impaired Neurological Activity in the Mental Rotation Ability of Tibetan Indigenous Residents After Chronic Exposure to High Altitude

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DOI	10.1016/j.neuroscience.2023.09.006
	Impaired Neurological Activity in the Mental Rotation Ability of Tibetan Indigenous Residents After Chronic Exposure to High Altitude
	Li, Xiaoyan; Ma, Hailin; Ding, Xiaobin; Jiang, Heng; Zhang, Xuemei
发表日期	2023
ISSN	0306-4522
EISSN	1873-7544
起始页码	1
结束页码	13
卷号	532
英文摘要	Mental rotation is a core indicator of spatial ability, and a threshold for cognitive impairment may exist at approximately 4,000 m above sea level, but the specific thresholds for the severity of hypoxia in Tibetan indigenous populations in mental rotation ability remain largely unknown. To determine whether a threshold for mental rotation impairment exists in indigenous residents, we related a mental rotation task to inter-individual differences in a range of behavioral performance and neuropsychological characteristics across 51 indigenous Tibetan highlanders and 34 matched controls at three different altitudes (sea level, 2,900 m, and 4,200 m). Analyses of reaction time showed delayed behavioral responses in the 4,200 m altitude group. Further analyses of rotation-related negativity (RRN) revealed that the RRN was significantly more negative and the differences disappeared gradually for different angles among individuals exposed to an altitude of 4,200 m. Moreover, a time-frequency analysis showed significantly enhanced alpha-and beta-band power values for the 4,200 m altitude participants after stimulus presentation. The impairment in mental rotation ability is related to hypoxia and can be attributed to the absence of sufficient cognitive resources, which demonstrates the existence of a threshold for the effects of high altitude on the brain's mental rotation ability. Taken together, our findings have important implications for exploring the altitude threshold for the influence of high-altitude exposure on brain function, as well as for guiding the development of innovative strategies to optimize the response of the organism against chronic hypoxia-induced under extreme environments. (c) 2023 IBRO. Published by Elsevier Ltd. All rights reserved.
关键词	high-altitude spatial ability mental rotation indigenous residents event-related potential.
英文关键词	WORKING-MEMORY; CEREBRAL PROCESSES; HYPOBARIC HYPOXIA; BRAIN POTENTIALS; SPATIAL ABILITY; EEG; RECOGNITION; TRANSFORMATIONS; OSCILLATIONS; METAANALYSIS
WOS研究方向	Neurosciences
WOS记录号	WOS:001149246200001
来源期刊	NEUROSCIENCE
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/283579
作者单位	Northwest Normal University - China; Tibet University; University of Electronic Science & Technology of China
推荐引用方式 GB/T 7714	Li, Xiaoyan,Ma, Hailin,Ding, Xiaobin,et al. Impaired Neurological Activity in the Mental Rotation Ability of Tibetan Indigenous Residents After Chronic Exposure to High Altitude[J],2023,532.
APA	Li, Xiaoyan,Ma, Hailin,Ding, Xiaobin,Jiang, Heng,&Zhang, Xuemei.(2023).Impaired Neurological Activity in the Mental Rotation Ability of Tibetan Indigenous Residents After Chronic Exposure to High Altitude.NEUROSCIENCE,532.
MLA	Li, Xiaoyan,et al."Impaired Neurological Activity in the Mental Rotation Ability of Tibetan Indigenous Residents After Chronic Exposure to High Altitude".NEUROSCIENCE 532(2023).