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DOI	10.1007/s13205-023-03720-x
	Current status of research on endophytes of traditional Tibetan medicinal plant and their metabolites
	Hu, Danni; Long, Xintong; Luobu, Tudan; Wang, Qi
发表日期	2023
ISSN	2190-572X
EISSN	2190-5738
卷号	13 期号:10
英文摘要	The Qinghai-Tibet Plateau, known as the Third Pole of the World, has a rich variety of medicinal plants that play an important role in the field of medicine due to its unique geographical environment. However, due to the limited resources of Tibetan medicinal plants and the fragility of the ecological environment of the Qinghai-Tibet Plateau, more and more Tibetan medicinal plants are on the verge of extinction. As a reservoir of biologically active metabolites, endophytes of medicinal plants produce a large number of compounds with potential applications in modern medicine (including antibacterial, immunosuppressive, antiviral, and anticancer) and are expected to be substitutes for Tibetan medicinal plants. This paper reviews 12 Tibetan medicinal plants from the Qinghai-Tibet Plateau, highlighting the diversity of their endophytes, the diversity of their metabolites and their applications. The results show that the endophytes of Tibetan medicinal plants are remarkably diverse, and the efficacy of their metabolites involves various aspects, such as antioxidant, anti-disease and anti-parasitic. In addition, conservation measures for the resources of Tibetan medicinal plants are summarised to provide a reference for an in-depth understanding of the endophytes of Tibetan medicinal plants and to stimulate the scientific community to bioprospect for the endophytes of Tibetan medicinal plants, as well as to provide ideas for their rational exploitation.
关键词	Qinghai-Tibet Plateau Tibetan medicinal plants Endophytes Metabolites Resource conservation
英文关键词	SAUSSUREA-MEDUSA; BACCATIN-III; FUNGUS; DIVERSITY; GROWTH; PODOPHYLLOTOXIN; PHYTOCHEMISTRY; CONSTITUENTS; PHARMACOLOGY; PEIMISINE
WOS研究方向	Biotechnology & Applied Microbiology
WOS记录号	WOS:001063422400003
来源期刊	3 BIOTECH
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/283213
作者单位	Wuhan University of Technology
推荐引用方式 GB/T 7714	Hu, Danni,Long, Xintong,Luobu, Tudan,et al. Current status of research on endophytes of traditional Tibetan medicinal plant and their metabolites[J],2023,13(10).
APA	Hu, Danni,Long, Xintong,Luobu, Tudan,&Wang, Qi.(2023).Current status of research on endophytes of traditional Tibetan medicinal plant and their metabolites.3 BIOTECH,13(10).
MLA	Hu, Danni,et al."Current status of research on endophytes of traditional Tibetan medicinal plant and their metabolites".3 BIOTECH 13.10(2023).