气候变化领域集成服务门户(CCPortal): Analysis of serum antioxidant capacity and gut microbiota in calves at different growth stages in Tibet

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DOI	10.3389/fmicb.2022.1089488
	Analysis of serum antioxidant capacity and gut microbiota in calves at different growth stages in Tibet
	Zhang, Xinyu; Cao, Zhijun; Yang, Hongjian; Wang, Yajing; Wang, Wei; Li, Shengli
发表日期	2023
EISSN	1664-302X
卷号	13
英文摘要	IntroductionThe hypoxic environment at high altitudes poses a major physiological challenge to animals, especially young animals, as it disturbs the redox state and induces intestinal dysbiosis. Information about its effects on Holstein calves is limited. MethodsHere, serum biochemical indices and next-generation sequencing were used to explore serum antioxidant capacity, fecal fermentation performance, and fecal microbiota in Holstein calves aged 1, 2, 3, 4, 5, and 6 months in Tibet. Results and DiscussionSerum antioxidant capacity changed with age, with the catalase and malondialdehyde levels significantly decreasing (p < 0.05), and superoxide dismutase levels significantly increasing (p < 0.05) with age. No significant differences (p > 0.05) in total volatile fatty acid levels were noted between the groups. In all groups, Firmicutes, Bacteroidetes, and Actinobacteria were the three most dominant phyla in the gut. Gut microbial alpha diversity significantly increased (p < 0.05) with age. Principal coordinate analysis plot based on Bray-Curtis dissimilarity revealed significant differences (p = 0.001) among the groups. Furthermore, the relative abundance of various genera changed dynamically with age, and the serum antioxidant capacity was associated with certain gut bacteria. The study provides novel insights for feeding Holstein calves in high-altitude regions.
关键词	gut microbiota Holstein calf high altitude antioxidant capacity different growth stages
英文关键词	MILK; GENOME; BIRTH; RUMEN; EVOLUTION; COMMUNITY; SEQUENCE; STRESS; BLOOD
WOS研究方向	Microbiology
WOS记录号	WOS:000931127800001
来源期刊	FRONTIERS IN MICROBIOLOGY
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/283138
作者单位	China Agricultural University
推荐引用方式 GB/T 7714	Zhang, Xinyu,Cao, Zhijun,Yang, Hongjian,et al. Analysis of serum antioxidant capacity and gut microbiota in calves at different growth stages in Tibet[J],2023,13.
APA	Zhang, Xinyu,Cao, Zhijun,Yang, Hongjian,Wang, Yajing,Wang, Wei,&Li, Shengli.(2023).Analysis of serum antioxidant capacity and gut microbiota in calves at different growth stages in Tibet.FRONTIERS IN MICROBIOLOGY,13.
MLA	Zhang, Xinyu,et al."Analysis of serum antioxidant capacity and gut microbiota in calves at different growth stages in Tibet".FRONTIERS IN MICROBIOLOGY 13(2023).