气候变化领域集成服务门户(CCPortal): Natural variation of codon repeats in COLD11 endows rice with chilling resilience

CCPortal

DOI	10.1126/sciadv.abq5506
	Natural variation of codon repeats in COLD11 endows rice with chilling resilience
	Li, Zhitao; Wang, Bo; Luo, Wei; Xu, Yunyuan; Wang, Jinjuan; Xue, Zhihui; Niu, Yuda; Cheng, Zhukuan; Ge, Song; Zhang, Wei; Zhang, Jingyu; Li, Qizhai; Chong, Kang
发表日期	2023
ISSN	2375-2548
卷号	9 期号:1
英文摘要	Abnormal temperature caused by global climate change threatens the rice production. Defense signaling network for chilling has been uncovered in plants. However, less is known about repairing DNA damage pro-duced from overwhelmed defense and its evolution during domestication. Here, we genetically identified a major QTL, COLD11, using the data-merging genome-wide association study based on an algorithm combining polarized data from two subspecies, indica and japonica, into one system. Rice loss-of-function mutations of COLD11 caused reduced chilling tolerance. Genome evolution analysis of representative rice germplasms sug-gested that numbers of GCG sequence repeats in the first exon of COLD11 were subjected to strong domesti-cation selection during the northern expansion of rice planting. The repeat numbers affected the biochemical activity of DNA repair protein COLD11/RAD51A1 in renovating DNA damage under chilling stress. Our findings highlight a potential way to finely manipulate key genes in rice genome and effectively improve chilling toler-ance through molecular designing.
语种	英语
WOS研究方向	Multidisciplinary Sciences
WOS类目	Science Citation Index Expanded (SCI-EXPANDED)
WOS记录号	WOS:000936020700018
来源期刊	SCIENCE ADVANCES
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/281363
作者单位	Chinese Academy of Sciences; Institute of Botany, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Beijing Institute of Technology; Chinese Academy of Sciences; Institute of Genetics & Developmental Biology, CAS; Yangzhou University; Chinese Academy of Sciences; Institute of Botany, CAS; Chinese Academy of Sciences
推荐引用方式 GB/T 7714	Li, Zhitao,Wang, Bo,Luo, Wei,et al. Natural variation of codon repeats in COLD11 endows rice with chilling resilience[J],2023,9(1).
APA	Li, Zhitao.,Wang, Bo.,Luo, Wei.,Xu, Yunyuan.,Wang, Jinjuan.,...&Chong, Kang.(2023).Natural variation of codon repeats in COLD11 endows rice with chilling resilience.SCIENCE ADVANCES,9(1).
MLA	Li, Zhitao,et al."Natural variation of codon repeats in COLD11 endows rice with chilling resilience".SCIENCE ADVANCES 9.1(2023).