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DOI	10.1038/s41559-021-01443-x
	A genome sequence from a modern human skull over 45,000 years old from Zlaty k?ň in Czechia
	Prüfer K.; Posth C.; Yu H.; Stoessel A.; Spyrou M.A.; Deviese T.; Mattonai M.; Ribechini E.; Higham T.; Velemínsky P.; Br??ek J.; Krause J.
发表日期	2021
ISSN	2397-334X
起始页码	820
结束页码	825
卷号	5 期号:6
英文摘要	Modern humans expanded into Eurasia more than 40,000 years ago following their dispersal out of Africa. These Eurasians carried ~2–3% Neanderthal ancestry in their genomes, originating from admixture with Neanderthals that took place sometime between 50,000 and 60,000 years ago, probably in the Middle East. In Europe, the modern human expansion preceded the disappearance of Neanderthals from the fossil record by 3,000–5,000 years. The genetic makeup of the first Europeans who colonized the continent more than 40,000 years ago remains poorly understood since few specimens have been studied. Here, we analyse a genome generated from the skull of a female individual from Zlaty k?ň, Czechia. We found that she belonged to a population that appears to have contributed genetically neither to later Europeans nor to Asians. Her genome carries ~3% Neanderthal ancestry, similar to those of other Upper Palaeolithic hunter-gatherers. However, the lengths of the Neanderthal segments are longer than those observed in the currently oldest modern human genome of the ~45,000-year-old Ust’-Ishim individual from Siberia, suggesting that this individual from Zlaty k?ň is one of the earliest Eurasian inhabitants following the expansion out of Africa. ? 2021, The Author(s).
语种	英语
scopus关键词	Africa; Czech Republic; Europe; female; human; Middle East; newborn; Russian Federation; skull; Africa; Czech Republic; Europe; Female; Humans; Infant, Newborn; Middle East; Siberia; Skull
来源期刊	Nature Ecology & Evolution
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/256946
作者单位	Max Planck Institute for the Science of Human History, Jena, Germany; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany; Institute for Archaeological Sciences, Archaeo- and Palaeogenetics, University of Tübingen, Tübingen, Germany; Institute of Zoology and Evolutionary Research, Friedrich Schiller University Jena, Jena, Germany; Oxford Radiocarbon Accelerator Unit, Research Laboratory for Archaeology and the History of Art, School of Archaeology, University of Oxford, Oxford, United Kingdom; Centre Européen de Recherche et d’Enseignement des Géosciences de l’Environnement (CEREGE), Aix-Marseille University, CNRS, IRD, INRAE, Collège de France, Aix-en-Provence, France; Department of Chemistry and Industrial Chemistry, University of Pisa, Pisa, Italy; Department of Anthropology, National Museum, Prague, Czech Republic; Department of Anthropology and Human Genetics, Faculty of Science, Charles University, Prague, Czech Republic
推荐引用方式 GB/T 7714	Prüfer K.,Posth C.,Yu H.,et al. A genome sequence from a modern human skull over 45,000 years old from Zlaty k?ň in Czechia[J],2021,5(6).
APA	Prüfer K..,Posth C..,Yu H..,Stoessel A..,Spyrou M.A..,...&Krause J..(2021).A genome sequence from a modern human skull over 45,000 years old from Zlaty k?ň in Czechia.Nature Ecology & Evolution,5(6).
MLA	Prüfer K.,et al."A genome sequence from a modern human skull over 45,000 years old from Zlaty k?ň in Czechia".Nature Ecology & Evolution 5.6(2021).