气候变化领域集成服务门户(CCPortal): Satellite DNA-mediated diversification of a sex-ratio meiotic drive gene family in Drosophila

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DOI	10.1038/s41559-021-01543-8
	Satellite DNA-mediated diversification of a sex-ratio meiotic drive gene family in Drosophila
	Muirhead C.A.; Presgraves D.C.
发表日期	2021
ISSN	2397-334X
起始页码	1604
结束页码	1612
卷号	5 期号:12
英文摘要	Sex chromosomes are susceptible to the evolution of selfish meiotic drive elements that bias transmission and distort progeny sex ratios. Conflict between such sex-ratio drivers and the rest of the genome can trigger evolutionary arms races resulting in genetically suppressed ‘cryptic’ drive systems. The Winters cryptic sex-ratio drive system of Drosophila simulans comprises a driver, Distorter on the X (Dox) and an autosomal suppressor, Not much yang, a retroduplicate of Dox that suppresses via production of endogenous small interfering RNAs (esiRNAs). Here we report that over 22 Dox-like (Dxl) sequences originated, amplified and diversified over the ~250,000-year history of the three closely related species, D. simulans, D. mauritiana and D. sechellia. The Dxl sequences encode a rapidly evolving family of protamines. Dxl copy numbers amplified by ectopic exchange among euchromatic islands of satellite DNAs on the X chromosome and separately spawned four esiRNA-producing suppressors on the autosomes. Our results reveal the genomic consequences of evolutionary arms races and highlight complex interactions among different classes of selfish DNAs. ? 2021, The Author(s), under exclusive licence to Springer Nature Limited.
语种	英语
scopus关键词	satellite DNA; animal; Drosophila; genetics; molecular evolution; sex ratio; X chromosome; Animals; DNA, Satellite; Drosophila; Evolution, Molecular; Sex Ratio; X Chromosome
来源期刊	Nature Ecology & Evolution
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/256816
作者单位	Department of Biology, University of Rochester, Rochester, NY, United States; Ronin Institute, Montclair, NJ, United States
推荐引用方式 GB/T 7714	Muirhead C.A.,Presgraves D.C.. Satellite DNA-mediated diversification of a sex-ratio meiotic drive gene family in Drosophila[J],2021,5(12).
APA	Muirhead C.A.,&Presgraves D.C..(2021).Satellite DNA-mediated diversification of a sex-ratio meiotic drive gene family in Drosophila.Nature Ecology & Evolution,5(12).
MLA	Muirhead C.A.,et al."Satellite DNA-mediated diversification of a sex-ratio meiotic drive gene family in Drosophila".Nature Ecology & Evolution 5.12(2021).