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DOI | 10.1016/j.saa.2021.119584 |
Fluorescent DNA-templated silver nanoclusters for highly sensitive detection of D-penicillamine | |
Liu, Lingyuan; Zhang, Qianyi; Li, Feng; Wang, Mei; Sun, Jing; Zhu, Shuyun | |
通讯作者 | Zhu, SY (通讯作者),Qufu Normal Univ, Sch Chem & Chem Engn, Qufu 273165, Shandong, Peoples R China. |
发表日期 | 2021 |
ISSN | 1386-1425 |
EISSN | 1873-3557 |
卷号 | 253 |
英文摘要 | Herein, fluorescent DNA-templated silver nanoclusters (DNA-AgNCs) with red emission were synthesized and utilized as novel probe to detect D-penicillamine (D-Pen) for the first time. D-Pen molecules contain a thiol which can combine with Ag to form a non-fluorescent ground state complex, inducing the aggregation of DNA-AgNCs followed by the fluorescence quenching. The quenching mechanism is well-studied and found to be a static quenching process. This method can detect D-Pen in the range of 0.025-0.7 mu M with the detection limit as low as 8 nM, which is 1-3 orders of magnitude more sensitive than those based on other fluorescent nanoprobes. More importantly, the preparation procedure for DNA-AgNCs is fast and without the requirement of heavy metal ions. Thus, this detection strategy is time-saving and eco-friendly. Satisfactory recoveries have been acquired for monitoring D-Pen in human serum samples and pharmaceutical samples owing to the high sensitivity. (C) 2021 Elsevier B.V. All rights reserved. |
英文关键词 | D-Penicillamine; DNA-templated synthesis; Silver nanoclusters; Static quenching; Fluorescence sensor |
语种 | 英语 |
WOS研究方向 | Spectroscopy |
WOS类目 | Spectroscopy |
WOS记录号 | WOS:000632454700002 |
来源期刊 | SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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来源机构 | 中国科学院西北生态环境资源研究院 |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/254581 |
作者单位 | [Liu, Lingyuan; Zhang, Qianyi; Wang, Mei; Zhu, Shuyun] Qufu Normal Univ, Sch Chem & Chem Engn, Qufu 273165, Shandong, Peoples R China; [Sun, Jing] Chinese Acad Sci, Northwest Inst Plateau Biol, Qinghai Key Lab Qinghai Tibet Plateau Biol Resour, Xining 810001, Peoples R China; [Li, Feng] Qingdao Special Serv Men Recuperat Ctr PLA Navy, Qingdao 266071, Peoples R China |
推荐引用方式 GB/T 7714 | Liu, Lingyuan,Zhang, Qianyi,Li, Feng,et al. Fluorescent DNA-templated silver nanoclusters for highly sensitive detection of D-penicillamine[J]. 中国科学院西北生态环境资源研究院,2021,253. |
APA | Liu, Lingyuan,Zhang, Qianyi,Li, Feng,Wang, Mei,Sun, Jing,&Zhu, Shuyun.(2021).Fluorescent DNA-templated silver nanoclusters for highly sensitive detection of D-penicillamine.SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,253. |
MLA | Liu, Lingyuan,et al."Fluorescent DNA-templated silver nanoclusters for highly sensitive detection of D-penicillamine".SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 253(2021). |
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