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DOI	10.1002/pca.3025
	Multivariate statistical and comparison analysis of chemical constituents in Arenaria kansuensis Maxim. from different regions in Qinghai-Tibet Plateau
	Liu, Zenggen; Li, Mingzhu; Tao, Yanduo; Olsen, Richard
通讯作者	Liu, ZG (通讯作者)，Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810001, Peoples R China.
发表日期	2021
ISSN	0958-0344
EISSN	1099-1565
起始页码	794
结束页码	803
卷号	32 期号:5
英文摘要	Introduction Arenaria kansuensis Maxim. (AKM) is one of the most valued medicinal and edible herbs widely used in Qinghai-Tibet Plateau and there is also a large number of AKM bioactive constituents for health benefits of human beings. However, few works have referred to phytochemical content, fingerprint analysis and quality control of AKM. Therefore, the establishment of validated analytical methods is urgently needed for fingerprint comparison and quantitative analysis of AKM multicomponent. Objectives To determine quantitatively and compare the phytochemical constituents of AKM located at different areas. Methodology The chemical constituents in AKM samples were separated, identified, and quantified by high-performance liquid chromatography (HPLC) with a diode array detector. The discrimination and separation models for the chemical constituents were developed by chemometric analysis. Results The flavones and beta-carboline alkaloids were rich in AKM herbs, and the overall pattern of phytochemical profiles was the same, while the significant differences were detected in the total flavonoids, total beta-carboline alkaloids and individual contents, especially the predominant compounds such as tricin and arenarine B. This demonstrated that ecogeographical origin gave an important impact on phytochemical compositions which could be considered as reliable parameters for classifying the AKM resources. Moreover, the contents of AKM constituents were higher in July and/or August than other months of the year, and there were no significant differences in the main phytochemical contents between cultivated and wild AKM herbs. Conclusion This study could provide credible data and method for geographical origin trace, comprehensive evaluation and further utilization of AKM resources.
英文关键词	Arenaria kansuensis Maxim; chemometric analysis; content variation; multivariate statistical analysis; phytochemical constituents
语种	英语
WOS研究方向	Biochemistry & Molecular Biology ; Plant Sciences ; Chemistry
WOS类目	Biochemical Research Methods ; Plant Sciences ; Chemistry, Analytical
WOS记录号	WOS:000612070400001
来源期刊	PHYTOCHEMICAL ANALYSIS
来源机构	中国科学院西北生态环境资源研究院
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/254032
作者单位	[Liu, Zenggen; Li, Mingzhu; Tao, Yanduo] Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810001, Peoples R China; [Liu, Zenggen; Li, Mingzhu; Tao, Yanduo] Qinghai Prov Key Lab Tibetan Med Res, Xining, Peoples R China; [Olsen, Richard] Univ Calif Los Angeles, David Geffen Sch Med, Dept Mol & Med Pharmacol, Los Angeles, CA 90095 USA
推荐引用方式 GB/T 7714	Liu, Zenggen,Li, Mingzhu,Tao, Yanduo,et al. Multivariate statistical and comparison analysis of chemical constituents in Arenaria kansuensis Maxim. from different regions in Qinghai-Tibet Plateau[J]. 中国科学院西北生态环境资源研究院,2021,32(5).
APA	Liu, Zenggen,Li, Mingzhu,Tao, Yanduo,&Olsen, Richard.(2021).Multivariate statistical and comparison analysis of chemical constituents in Arenaria kansuensis Maxim. from different regions in Qinghai-Tibet Plateau.PHYTOCHEMICAL ANALYSIS,32(5).
MLA	Liu, Zenggen,et al."Multivariate statistical and comparison analysis of chemical constituents in Arenaria kansuensis Maxim. from different regions in Qinghai-Tibet Plateau".PHYTOCHEMICAL ANALYSIS 32.5(2021).