气候变化领域集成服务门户(CCPortal): The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis

CCPortal

DOI	10.1038/s41467-021-23112-0
	The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis
	Vu L.D.; Xu X.; Zhu T.; Pan L.; van Zanten M.; de Jong D.; Wang Y.; Vanremoortele T.; Locke A.M.; van de Cotte B.; De Winne N.; Stes E.; Russinova E.; De Jaeger G.; Van Damme D.; Uauy C.; Gevaert K.; De Smet I.
发表日期	2021
ISSN	2041-1723
卷号	12 期号:1
英文摘要	Plants respond to mild warm temperature conditions by increased elongation growth of organs to enhance cooling capacity, in a process called thermomorphogenesis. To this date, the regulation of thermomorphogenesis has been exclusively shown to intersect with light signalling pathways. To identify regulators of thermomorphogenesis that are conserved in flowering plants, we map changes in protein phosphorylation in both dicots and monocots exposed to warm temperature. We identify MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE4 (MAP4K4)/TARGET OF TEMPERATURE3 (TOT3) as a regulator of thermomorphogenesis that impinges on brassinosteroid signalling in Arabidopsis thaliana. In addition, we show that TOT3 plays a role in thermal response in wheat, a monocot crop. Altogether, the conserved thermal regulation by TOT3 expands our knowledge of thermomorphogenesis beyond the well-studied pathways and can contribute to ensuring food security under a changing climate. © 2021, The Author(s).
语种	英语
scopus关键词	brassinosteroid; mitogen activated protein kinase kinase kinase kinase 4; protein kinase; target of temperature 3; unclassified drug; Arabidopsis protein; basic helix loop helix transcription factor; PHYB protein, Arabidopsis; phytochrome B; phytohormone; PIF4 protein, Arabidopsis; protein serine threonine kinase; climate change; detection method; enzyme; enzyme activity; food security; geomembrane; growth; herb; membrane; protein; temperature effect; Arabidopsis thaliana; Article; climate change; controlled study; environmental temperature; enzyme activity; eudicot; food security; monocot; nonhuman; phosphoproteomics; plant growth; protein function; protein localization; protein phosphorylation; thermoregulation; wheat; acclimatization; Arabidopsis; gene expression regulation; genetics; growth, development and aging; metabolism; phosphorylation; physiology; plant development; signal transduction; temperature; transgenic plant; Arabidopsis thaliana; Dicotyledoneae; Liliopsida; Magnoliophyta; Acclimatization; Arabidopsis; Arabidopsis Proteins; Basic Helix-Loop-Helix Transcription Factors; Brassinosteroids; Gene Expression Regulation, Plant; Phosphorylation; Phytochrome B; Plant Development; Plant Growth Regulators; Plants, Genetically Modified; Protein-Serine-Threonine Kinases; Signal Transduction; Temperature
来源期刊	Nature Communications
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/251449
作者单位	Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, B-9052, Belgium; VIB Center for Plant Systems Biology, Ghent, B-9052, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, B-9000, Belgium; VIB Center for Medical Biotechnology, Ghent, B-9000, Belgium; Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, Utrecht, 3584CH, Netherlands; Soybean & Nitrogen Fixation Research Unit, United States Department of Agriculture- Agricultural Research Service, Raleigh, NC 27695, United States; Department of Crop and Soil Sciences, North Carolina State University, Raleigh, NC 27695, United States; Department of Crop Genetics, John Innes Centre, Norwich Research ParkNR4 7UH, United Kingdom; VIB Headquarters, Gent, 9052, Belgium
推荐引用方式 GB/T 7714	Vu L.D.,Xu X.,Zhu T.,et al. The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis[J],2021,12(1).
APA	Vu L.D..,Xu X..,Zhu T..,Pan L..,van Zanten M..,...&De Smet I..(2021).The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis.Nature Communications,12(1).
MLA	Vu L.D.,et al."The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis".Nature Communications 12.1(2021).