气候变化领域集成服务门户(CCPortal): Modelling the persistence and control of Rift Valley fever virus in a spatially heterogeneous landscape

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DOI	10.1038/s41467-021-25833-8
	Modelling the persistence and control of Rift Valley fever virus in a spatially heterogeneous landscape
	Tennant W.S.D.; Cardinale E.; Cêtre-Sossah C.; Moutroifi Y.; Le Godais G.; Colombi D.; Spencer S.E.F.; Tildesley M.J.; Keeling M.J.; Charafouddine O.; Colizza V.; Edmunds W.J.; Métras R.
发表日期	2021
ISSN	2041-1723
卷号	12 期号:1
英文摘要	The persistence mechanisms of Rift Valley fever (RVF), a zoonotic arboviral haemorrhagic fever, at both local and broader geographical scales have yet to be fully understood and rigorously quantified. We developed a mathematical metapopulation model describing RVF virus transmission in livestock across the four islands of the Comoros archipelago, accounting for island-specific environments and inter-island animal movements. By fitting our model in a Bayesian framework to 2004–2015 surveillance data, we estimated the importance of environmental drivers and animal movements on disease persistence, and tested the impact of different control scenarios on reducing disease burden throughout the archipelago. Here we report that (i) the archipelago network was able to sustain viral transmission in the absence of explicit disease introduction events after early 2007, (ii) repeated outbreaks during 2004–2020 may have gone under-detected by local surveillance, and (iii) co-ordinated within-island control measures are more effective than between-island animal movement restrictions. © 2021, The Author(s).
语种	英语
scopus关键词	immunoglobulin G; archipelago; environmental factor; heterogeneity; livestock; metapopulation; rift zone; virus; age; animal experiment; Article; basic reproduction number; Bayesian network; bovine; Comoros; controlled study; disease burden; disease surveillance; environmental factor; epidemic; goat; infection control; island (geological); livestock; mathematical model; metapopulation; mortality rate; nonhuman; Rift Valley fever; Rift Valley fever virus; seroprevalence; sheep; shipping; virus transmission; animal; physiology; Rift Valley fever; Rift Valley fever virus; seroepidemiology; theoretical model; virology; zoonosis; Comoros; Kenya; Rift Valley; Rift Valley fever virus; Animals; Comoros; Livestock; Models, Theoretical; Rift Valley Fever; Rift Valley fever virus; Seroepidemiologic Studies; Zoonoses
来源期刊	Nature Communications
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/251350
作者单位	The Zeeman Institute: SBIDER, University of Warwick, Coventry, CV4 7AL, United Kingdom; Mathematics Institute, University of Warwick, Coventry, CV4 7AL, United Kingdom; Centre de Coopération Internationale en Recherche Agronomique pour le Développement, UMR Animal, Santé, Territoires, Risques, et Écosystèmes, Sainte Clotilde, La Réunion, F-97490, France; Animal, Santé, Territoires, Risques, et Écosystèmes, Université de Montpellier, Centre de Coopération Internationale en Recherche Agronomique pour le Développement, INRAE, Montpellier, France; Vice-Présidence en charge de l’Agriculture, l’Elevage, la Pêche, l’Industrie, l’Energie et l’Artisanat, B.P. 41 Mdé, Moroni, Comoros; Direction de l’Alimentation, de l’Agriculture et de la Forêt de Mayotte, Service de l’Alimentation, Mamoudzou, 97600, France; Aizoon Technology Consulting, Str. del Lionetto 6, Torino, Italy; Department of Statistics, University of Warwick, Coventry, CV4, 7AL, United Kingdom; School of Life Sciences, University of Warwick, Coventry, C...
推荐引用方式 GB/T 7714	Tennant W.S.D.,Cardinale E.,Cêtre-Sossah C.,et al. Modelling the persistence and control of Rift Valley fever virus in a spatially heterogeneous landscape[J],2021,12(1).
APA	Tennant W.S.D..,Cardinale E..,Cêtre-Sossah C..,Moutroifi Y..,Le Godais G..,...&Métras R..(2021).Modelling the persistence and control of Rift Valley fever virus in a spatially heterogeneous landscape.Nature Communications,12(1).
MLA	Tennant W.S.D.,et al."Modelling the persistence and control of Rift Valley fever virus in a spatially heterogeneous landscape".Nature Communications 12.1(2021).