气候变化领域集成服务门户(CCPortal): Air pollutants concentration and variation of blood glucose level among pregnant women in China: A cross-sectional study

CCPortal

DOI	10.1016/j.atmosenv.2019.117191
	Air pollutants concentration and variation of blood glucose level among pregnant women in China: A cross-sectional study
	Li D.; Wang J.-B.; Yu Z.-B.; Lin H.-B.; Chen K.
发表日期	2020
ISSN	1352-2310
卷号	223
英文摘要	Air pollution has been reported to be associated with the risk of type 2 diabetes, but no previous study has investigated the association with changes in blood glucose levels in pregnant women in China. We aimed to examine the associations of air pollution concentration with blood glucose among pregnant women. We identified 37,383 women who were pregnant from hospital records from January 2013 to July 2017. We used generalized linear models to estimate adverse associations of air pollution on the glucose challenge test (GCT) and oral glucose tolerance test (OGTT) blood glucose levels among pregnant women in the second trimester on lag days 1–7, adjusting for a number of demographics, health and socioeconomic covariates. An IQR increase in PM2.5 concentration during the second trimester was associated with 2.09% (7-day lag, 95% CI: 1.62%, 2.57%) higher GCT blood glucose levels; the corresponding figures for PM10, NO2 and CO were 3.99% (7-day lag, 95% CI: 3.28%, 4.71%), 7.40% (6-day lag, 95% CI: 6.41%, 8.39%), and 4.23% (4-day lag, 95% CI: 3.75%, 4.71%), respectively. For PM2.5, PM10 and NO2 concentrations, significant associations were observed among women with older age, overweight/obesity, and lower education level. However, pregnant women with lower BMI were more susceptible to higher CO-related GCT blood glucose levels. Participants who worked as public servants and technicians may be less susceptible to the effects of PM2.5, PM10, NO2 and CO than women with the other three occupations considered. Too much or too little exercise frequency was susceptible to the adverse effects of air pollution in pregnant women (higher blood glucose levels). Our estimates for air pollutants and OGTT were generally consistent with the corresponding β values for GCT blood glucose. In the present study, women had higher blood glucose levels when exposed to higher residential PM2.5, PM10, NO2 and CO during their pregnancy. Women with higher BMI and lower education levels were more susceptible to the adverse effects of ambient air pollution. © 2019
关键词	Air pollutants GCT OGTT Pregnant women
语种	英语
scopus关键词	Blood; Glucose; Nitrogen oxides; Air pollutants; Ambient air pollution; Cross-sectional study; Generalized linear model; OGTT; Oral glucose tolerance tests; Pollution concentration; Pregnant woman; Air pollution; carbon monoxide; glucose; nitrogen dioxide; ozone; sulfur dioxide; ambient air; atmospheric pollution; blood; glucose; health risk; pregnancy; risk factor; womens health; adult; air pollution; ambient air; body mass; China; civil servant; cross-sectional study; demography; educational status; female; glucose blood level; housewife; human; major clinical study; manual labor; medical information system; medical record; obesity; oral glucose tolerance test; particulate matter; physician; pregnant woman; prenatal period; priority journal; provocation test; second trimester pregnancy; socioeconomics; China
来源期刊	ATMOSPHERIC ENVIRONMENT
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/249394
作者单位	Department of Epidemiology and Health Statistics, Zhejiang University School of Public Health, NO. 866 Yuhangtang Road, Xihu District, Hangzhou, Zhejiang, China; Research Center for Air Pollution and Health, Zhejiang University, Hangzhou, Zhejiang 310058, China; Center for Disease Control and Prevention of Yinzhou District, Ningbo, Zhejiang 315100, China; Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China
推荐引用方式 GB/T 7714	Li D.,Wang J.-B.,Yu Z.-B.,et al. Air pollutants concentration and variation of blood glucose level among pregnant women in China: A cross-sectional study[J],2020,223.
APA	Li D.,Wang J.-B.,Yu Z.-B.,Lin H.-B.,&Chen K..(2020).Air pollutants concentration and variation of blood glucose level among pregnant women in China: A cross-sectional study.ATMOSPHERIC ENVIRONMENT,223.
MLA	Li D.,et al."Air pollutants concentration and variation of blood glucose level among pregnant women in China: A cross-sectional study".ATMOSPHERIC ENVIRONMENT 223(2020).