气候变化领域集成服务门户(CCPortal): Size-specific particulate air pollution and hospitalization for cardiovascular diseases: A case-crossover study in Shenzhen, China

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DOI	10.1016/j.atmosenv.2021.118271
	Size-specific particulate air pollution and hospitalization for cardiovascular diseases: A case-crossover study in Shenzhen, China
	Zhang Y.; Zhang L.; Wei J.; Liu L.; Wang Y.; Liu J.; Zhou P.; Wang L.; Ding Z.; Zhang Y.
发表日期	2021
ISSN	1352-2310
卷号	251
英文摘要	Background: Despite contributing to the majority of ambient fine particles (PM2.5), PM1 (particulate matter [PM] with aerodynamic diameter ≤1 μm) remains poorly studied in terms of its acute effects on cardiovascular diseases (CVDs) in China. This study aims to evaluate the short-term associations of size-specific PMs (i.e., PM1, PM2.5, and PM10) exposures with hospital admissions for CVDs in a southern Chinese metropolis. Methods: We collected 5,969 records of hospital admissions for CVDs and daily average concentrations of air pollutants and weather conditions in Shenzhen from January 1st 2015 to December 31st 2017. We adopted a time-stratified case-crossover design and conditional logistic regression models to assess short-term associations between size-specific PMs and CVD hospitalizations along different exposure days. Results: During the study period, annual average concentrations of PM1, PM2.5, and PM10 were 18.7, 27.8, and 45.4 μg/m3, respectively. Compared to PM2.5 and PM10, PM1 exhibited a generally stronger association with CVD hospitalizations. Hospital admissions for CVDs increased by 6.7% (95% confidence interval: 1.2–12.5%), 4.5% (0.4–8.7%), and 3.4% (0.5–6.3%), corresponding to per 10-μg/m3 rise in exposure to PM1, PM2.5, and PM10 at lag 03 days. In our stratified analyses by CVD sub-causes, size-specific PMs showed consistent effects on hypertension but no evident association with ischemic heart disease (IHD) and stroke. Seasonal analysis revealed significantly larger PM-associated risks among IHD patients in cold months (October–March). Nevertheless, in warm months (April–September), the older group (aged 65+ years) was more prone to adverse effects of PM1 exposure at lag 0 day. Conclusion: Short-term exposure to size-specific PMs, PM1 in particular, may trigger incidences of CVD hospitalization. To effectively mitigate adverse effects of particulate pollution, evidence-based PM1 standards should be developed as well in Chinese less-polluted megacities. © 2021 Elsevier Ltd
关键词	Cardiovascular diseases Case-crossover study Fine particulate matter PM1 Short-term impact
语种	英语
scopus关键词	Air quality; Cardiology; Diseases; Hospitals; Logistic regression; Particle size analysis; Risk assessment; Aerodynamic diameters; Annual average concentration; Average concentration; Cardio-vascular disease; Case-crossover designs; Conditional logistic regressions; Ischemic heart disease; Particulate air pollution; Particles (particulate matter); aerodynamics; air quality; atmospheric pollution; cardiovascular disease; correlation; hospital sector; metropolitan area; particle size; particulate matter; pollution effect; pollution exposure; public health; adult; aged; air pollutant; air pollution; Article; cerebrovascular accident; China; controlled study; crossover procedure; female; hospital admission; hospitalization; human; hypertension; ischemic heart disease; major clinical study; male; middle aged; particulate matter 1; particulate matter 10; particulate matter 2.5; priority journal; respirable particulate matter; seasonal variation; China; Guangdong; Shenzhen
来源期刊	ATMOSPHERIC ENVIRONMENT
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/248530
作者单位	Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University of Science and Technology, Wuhan, 430065, China; State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University, Beijing, China; Department of Atmospheric and Oceanic Science, Earth System Science Interdisciplinary Center, University of Maryland, College ParkMD, United States; Department of Nursing, Medical College, Wuhan University of Science and Technology, Wuhan, 430065, China; The Institute of Metabolic Diseases, Baoan Central Hospital of Shenzhen, The Fifth Affiliated Hospital of Shenzhen University, Shenzhen, 518102, China; Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, 430065, China
推荐引用方式 GB/T 7714	Zhang Y.,Zhang L.,Wei J.,et al. Size-specific particulate air pollution and hospitalization for cardiovascular diseases: A case-crossover study in Shenzhen, China[J],2021,251.
APA	Zhang Y..,Zhang L..,Wei J..,Liu L..,Wang Y..,...&Zhang Y..(2021).Size-specific particulate air pollution and hospitalization for cardiovascular diseases: A case-crossover study in Shenzhen, China.ATMOSPHERIC ENVIRONMENT,251.
MLA	Zhang Y.,et al."Size-specific particulate air pollution and hospitalization for cardiovascular diseases: A case-crossover study in Shenzhen, China".ATMOSPHERIC ENVIRONMENT 251(2021).