气候变化领域集成服务门户(CCPortal): Long-term air pollution exposure and serum lipids and blood sugar: A longitudinal cohort study from the electricity generating authority of Thailand study

CCPortal

DOI	10.1016/j.atmosenv.2021.118515
	Long-term air pollution exposure and serum lipids and blood sugar: A longitudinal cohort study from the electricity generating authority of Thailand study
	Paoin K.; Ueda K.; Vathesatogkit P.; Ingviya T.; Buya S.; Phosri A.; Seposo X.T.; Thongmung N.; Yingchoncharoen T.; Honda A.; Takano H.; Sritara P.
发表日期	2021
ISSN	1352-2310
卷号	259
英文摘要	Only a few studies have investigated the association between long-term exposure to air pollution and alterations of serum lipids and blood sugar level in developing countries. The present longitudinal study examined associations between long-term air pollution exposure and serum lipids [total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C)] and fasting glucose (FG) in workers of the Electricity Generating Authority of Thailand (EGAT) in the Bangkok metropolitan region (BMR) of Thailand. We performed secondary analyses using the data obtained from 1,839 participants (mean age, 58.3 years as of 2002) of the EGAT1 cohort study (2002–2012). The average concentration of each air pollutants (PM10, O3, NO2, SO2, and CO) at the sub-district level in BMR from 2002 to 2012 were estimated using the ordinary kriging method. Exposure periods were averaged to 3 months prior to laboratory testing. Linear mixed effects models were used to estimate associations between air pollution and serum lipids and blood sugar. After controlling for potential confounders, an interquartile range increment of PM10, SO2, and CO was associated with elevated LDL-C [6.6% (95%CI: 4.3, 9.0), 11.1% (7.2, 15.2), and 1.9% (1.1, 2.7), respectively] and FG [2.8% (1.5, 4.2), 6.8% (4.5, 9.1), and 1.1% (0.6, 1.5), respectively]. In addition, PM10, SO2, and CO were inversely associated with HDL-C [-1.8% (−3.7, 0.1), −3.3% (−6.2, −0.3), and −1.1 (−1.7, −0.5), respectively]. O3 was negatively associated with TC, LDL-C, TG, and FG. These findings suggest inhalation of air pollutants may increase the risk of impaired metabolism of glucose and lipids. © 2021 Elsevier Ltd
关键词	Air pollution Blood sugar Long-term exposure Longitudinal study Serum lipids
语种	英语
scopus关键词	Blood; Cholesterol; Developing countries; Electric power generation; Glucose; Lipoproteins; Air pollution exposures; Blood sugars; Cohort studies; Lipoprotein cholesterol; Long term exposure; Longitudinal study; Low density lipoproteins; PM$-10$; Serum lipid; SO$-2$; Air pollution; glucose; high density lipoprotein cholesterol; lipid; low density lipoprotein cholesterol; triacylglycerol; atmospheric pollution; authoritarianism; cohort analysis; concentration (composition); electricity generation; health risk; lipid; pollution exposure; serum; sugar; adult; air pollutant; air pollution; air quality; Article; basal metabolic rate; blood sampling; body mass; cholesterol blood level; cohort analysis; controlled study; diabetes education; diabetes mellitus; electricity; female; follow up; glucose blood level; glucose metabolism; hip circumference; human; humidity; hypercholesterolemia; hypertension; kriging; laboratory test; leave one out cross validation; lipid blood level; lipid metabolism; long term exposure; longitudinal study; major clinical study; male; middle aged; middle income group; people by smoking status; physical examination; prevalence; Thailand; Bangkok; Central Region [Thailand]; Krung Thep Mahanakhon; Thailand; Thailand
来源期刊	ATMOSPHERIC ENVIRONMENT
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/248366
作者单位	Department of Environmental Engineering, Graduate School of Engineering, Kyoto University, Kyoto, Japan; Graduate School of Global Environmental Sciences, Kyoto University, Kyoto, Japan; Department of Internal Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Department of Family and Preventive Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand; Medical Data Center for Research and Innovation, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand; Department of Environmental Health Sciences, Faculty of Public Health, Mahidol University, Bangkok, Thailand; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan; Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Air Pollution and Health Effect Research Center, Prince of Songkla University, Songkhla, Thailand
推荐引用方式 GB/T 7714	Paoin K.,Ueda K.,Vathesatogkit P.,et al. Long-term air pollution exposure and serum lipids and blood sugar: A longitudinal cohort study from the electricity generating authority of Thailand study[J],2021,259.
APA	Paoin K..,Ueda K..,Vathesatogkit P..,Ingviya T..,Buya S..,...&Sritara P..(2021).Long-term air pollution exposure and serum lipids and blood sugar: A longitudinal cohort study from the electricity generating authority of Thailand study.ATMOSPHERIC ENVIRONMENT,259.
MLA	Paoin K.,et al."Long-term air pollution exposure and serum lipids and blood sugar: A longitudinal cohort study from the electricity generating authority of Thailand study".ATMOSPHERIC ENVIRONMENT 259(2021).