气候变化领域集成服务门户(CCPortal): Short-term exposure to air pollutants increases the risk of hospital admissions in patients with Parkinson's disease

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DOI	10.1016/j.atmosenv.2021.118668
	Short-term exposure to air pollutants increases the risk of hospital admissions in patients with Parkinson's disease – A multicentric study on 18 French areas
	Goria S.; Pascal M.; Corso M.; Le Tertre A.
发表日期	2021
ISSN	1352-2310
卷号	264
英文摘要	Background: Recent studies have investigated the potential neurological impacts of short-term exposure to air pollutants, but with limited evidence. Objective: To analyze the relationship and quantify the short-term association of air pollution (PM10, PM2.5, NO2 and ozone) and hospital admissions for Parkinson's disease (PD), in 18 French areas. Methods: We modeled the daily number of PD-related hospital admissions in each area using a generalized additive Poisson regression model for the 2009–2017 period, introducing air pollutants as the main environmental variable and daily temperature as covariate. We controlled for long-term trend and seasonality. Results: A small but significant influence of PM10, PM2.5 and NO2 on all-ages PD hospital admissions was observed, of a similar order of magnitude (1.010 [95% CI: 1.004; 1.016], 1.010 [1.003; 1.017], and 1.011 [1.005; 1.016] for a 10 μg/m3 increase in PM10, PM2.5 and NO2, respectively). We also found an increase in hospitalization risks, at the limit of significance, associated with ozone (1.001 [95% CI: 0.999; 1.004]). Conclusion: Our results suggest a short-term association between PM, NO2, ozone and daily hospital admissions due to PD. © 2021 Elsevier Ltd
关键词	Air pollution Exacerbation Morbidity Parkinson's disease
语种	英语
scopus关键词	Hospitals; Neurodegenerative diseases; Nitrogen oxides; Ozone; Regression analysis; Air pollutants; Exacerbation; Hospital admissions; NO $-2$; Parkinson's disease; PM$-10$; PM$-2.5$; Short term; Short-term exposure; Term associations; Air pollution; atmospheric pollution; disease prevalence; health risk; nervous system disorder; pollution exposure; France
来源期刊	ATMOSPHERIC ENVIRONMENT
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/248246
作者单位	Santé publique France, 12 rue du Val D'Osne, Saint Maurice, 94415, France
推荐引用方式 GB/T 7714	Goria S.,Pascal M.,Corso M.,等. Short-term exposure to air pollutants increases the risk of hospital admissions in patients with Parkinson's disease – A multicentric study on 18 French areas[J],2021,264.
APA	Goria S.,Pascal M.,Corso M.,&Le Tertre A..(2021).Short-term exposure to air pollutants increases the risk of hospital admissions in patients with Parkinson's disease – A multicentric study on 18 French areas.ATMOSPHERIC ENVIRONMENT,264.
MLA	Goria S.,et al."Short-term exposure to air pollutants increases the risk of hospital admissions in patients with Parkinson's disease – A multicentric study on 18 French areas".ATMOSPHERIC ENVIRONMENT 264(2021).