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DOI	10.1126/science.aaz1293
	Direct synthesis of adipic acid esters via palladium-catalyzed carbonylation of 1,3-dienes
	Yang J.; Liu J.; Neumann H.; Franke R.; Jackstell R.; Beller M.
发表日期	2019
ISSN	0036-8075
起始页码	1514
结束页码	1517
卷号	366 期号:6472
英文摘要	The direct carbonylation of 1,3-butadiene offers the potential for a more cost-efficient and environmentally benign route to industrially important adipic acid derivatives. However, owing to the complex reaction network of regioisomeric carbonylation and isomerization pathways, a selective practical catalyst for this process has thus far proven elusive. Here, we report the design of a pyridyl-substituted bidentate phosphine ligand (HeMaRaphos) that, upon coordination to palladium, catalyzes adipate diester formation from 1,3-butadiene, carbon monoxide, and butanol with 97% selectivity and 100% atom-economy under industrially viable and scalable conditions (turnover number > 60,000). This catalyst system also affords access to a variety of other di- and triesters from 1,2- and 1,3-dienes. © 2019 American Association for the Advancement of Science. All rights reserved.
英文关键词	1,2 butadiene; 1,3 butadiene; adipic acid; butanol; carbon monoxide; ester; ligand; palladium; pyridyl substituted bidentate phosphine ligand; unclassified drug; carbon monoxide; catalyst; design; ligand; organic acid; Article; carbonylation; catalyst; chemical structure; priority journal; process design; regioselectivity; structure analysis; synthesis; turnover number
语种	英语
来源期刊	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/246095
作者单位	Leibniz-Institut für Katalyse e.V. an der, Universität Rostock, Albert-Einstein Str. 29a, Rostock, D-18059, Germany; Evonik Performance Materials GmbH, Paul-Baumann-Str. 1, Marl, 45772, Germany; Theoretical Chemistry, Ruhr-University Bochum, Bochum, 44780, Germany
推荐引用方式 GB/T 7714	Yang J.,Liu J.,Neumann H.,et al. Direct synthesis of adipic acid esters via palladium-catalyzed carbonylation of 1,3-dienes[J],2019,366(6472).
APA	Yang J.,Liu J.,Neumann H.,Franke R.,Jackstell R.,&Beller M..(2019).Direct synthesis of adipic acid esters via palladium-catalyzed carbonylation of 1,3-dienes.Science,366(6472).
MLA	Yang J.,et al."Direct synthesis of adipic acid esters via palladium-catalyzed carbonylation of 1,3-dienes".Science 366.6472(2019).