气候变化领域集成服务门户(CCPortal): A single fungal MAP kinase controls plant cell-to-cell invasion by the rice blast fungus

CCPortal

DOI	10.1126/science.aaq0892
	A single fungal MAP kinase controls plant cell-to-cell invasion by the rice blast fungus
	Sakulkoo W.; Osés-Ruiz M.; Garcia E.O.; Soanes D.M.; Littlejohn G.R.; Hacker C.; Correia A.; Valent B.; Talbot N.J.
发表日期	2018
ISSN	0036-8075
起始页码	1399
结束页码	1403
卷号	359 期号:6382
英文摘要	Blast disease destroys up to 30% of the rice crop annually and threatens global food security. The blast fungus Magnaporthe oryzae invades plant tissue with hyphae that proliferate and grow from cell to cell, often through pit fields, where plasmodesmata cluster. We showed that chemical genetic inhibition of a single fungal mitogen-activated protein (MAP) kinase, Pmk1, prevents M. oryzae from infecting adjacent plant cells, leaving the fungus trapped within a single plant cell. Pmk1 regulates expression of secreted fungal effector proteins implicated in suppression of host immune defenses, preventing reactive oxygen species generation and excessive callose deposition at plasmodesmata. Furthermore, Pmk1 controls the hyphal constriction required for fungal growth from one rice cell to the neighboring cell, enabling host tissue colonization and blast disease. © 2017 The Authors.
英文关键词	mitogen activated protein kinase; protein Pmk1; reactive oxygen metabolite; unclassified drug; mitogen activated protein kinase; cell; colonization; fungus; gene expression; immune response; inhibition; protein; reactive oxygen species; rice; Article; cell invasion; fungal colonization; fungal plant disease; fungus hyphae; immune response; Magnaporthe oryzae; nonhuman; plant cell; plant defense; plant fungus interaction; plasmodesma; priority journal; protein expression; protein secretion; disease resistance; enzymology; genetics; growth, development and aging; host pathogen interaction; immunology; Magnaporthe; microbiology; Oryza; pathogenicity; physiology; plant cell; plant disease; Fungi; Magnaporthe grisea; Magnaporthe oryzae; Disease Resistance; Host-Pathogen Interactions; Hyphae; Magnaporthe; Mitogen-Activated Protein Kinases; Oryza; Plant Cells; Plant Diseases
语种	英语
来源期刊	Science
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/245322
作者单位	School of Biosciences, University of Exeter, Exeter, EX4 4QD, United Kingdom; Department of Plant Pathology, Kansas State University, 4024 Throckmorton Plant Sciences Center, Manhattan, KS 66506-5502, United States; School of Biological and Marine Sciences, Plymouth University, Portland Square Building, Drake Circus, Plymouth, PL4 8AA, United Kingdom
推荐引用方式 GB/T 7714	Sakulkoo W.,Osés-Ruiz M.,Garcia E.O.,et al. A single fungal MAP kinase controls plant cell-to-cell invasion by the rice blast fungus[J],2018,359(6382).
APA	Sakulkoo W..,Osés-Ruiz M..,Garcia E.O..,Soanes D.M..,Littlejohn G.R..,...&Talbot N.J..(2018).A single fungal MAP kinase controls plant cell-to-cell invasion by the rice blast fungus.Science,359(6382).
MLA	Sakulkoo W.,et al."A single fungal MAP kinase controls plant cell-to-cell invasion by the rice blast fungus".Science 359.6382(2018).