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DOI10.1126/science.abd7672
Epidemiology and transmission dynamics of COVID-19 in two Indian states
Laxminarayan R.; Wahl B.; Dudala S.R.; Gopal K.; Mohan C.B.; Neelima S.; Jawahar Reddy K.S.; Radhakrishnan J.; Lewnard J.A.
发表日期2020
ISSN0036-8075
卷号370期号:6517
英文摘要Although most cases of coronavirus disease 2019 (COVID-19) have occurred in low-resource countries, little is known about the epidemiology of the disease in such contexts. Data from the Indian states of Tamil Nadu and Andhra Pradesh provide a detailed view into severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission pathways and mortality in a high-incidence setting. Reported cases and deaths have been concentrated in younger cohorts than would be expected from observations in higher-income countries, even after accounting for demographic differences across settings. Among 575,071 individuals exposed to 84,965 confirmed cases, infection probabilities ranged from 4.7 to 10.7% for low-risk and high-risk contact types, respectively. Same-age contacts were associated with the greatest infection risk. Case fatality ratios spanned 0.05% at ages of 5 to 17 years to 16.6% at ages of 85 years or more. Primary data from low-resource countries are urgently needed to guide control measures. © 2020 American Association for the Advancement of Science. All rights reserved.
英文关键词cohort analysis; disease incidence; epidemic; epidemiology; health risk; infectious disease; mortality; severe acute respiratory syndrome; age distribution; Article; case fatality rate; contact examination; coronavirus disease 2019; demography; disease surveillance; epidemic; epidemiological data; geographic distribution; high income country; high risk population; highest income group; human; incidence; India; infection risk; low income country; low risk population; morbidity; mortality; nonhuman; priority journal; Severe acute respiratory syndrome coronavirus 2; survival rate; trend study; virus transmission; adolescent; adult; aged; Betacoronavirus; child; Coronavirus infection; epidemiology; female; infant; male; middle aged; mortality; newborn; pandemic; preschool child; very elderly; virus pneumonia; young adult; Andhra Pradesh; India; Tamil Nadu; Coronavirus; SARS coronavirus; Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Betacoronavirus; Child; Child, Preschool; Contact Tracing; Coronavirus Infections; Female; Humans; Incidence; India; Infant; Infant, Newborn; Male; Middle Aged; Pandemics; Pneumonia, Viral; Young Adult
语种英语
来源期刊Science
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/244473
作者单位Center for Disease Dynamics, Economics and Policy, New Delhi, India; Princeton Environmental Institute, Princeton University, Princeton, NJ, United States; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States; International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States; Department of Community Medicine, Government Medical College, Kadapa, Andhra Pradesh, India; Animal Husbandry, Dairying and Fisheries Department, Government of Tamil Nadu, Chennai, Tamil Nadu, India; Backward Classes, Most Backward Classes, Minorities Welfare Department, Government of Tamil Nadu, Chennai, Tamil Nadu, India; Department of Community Medicine, Guntur Medical College, Guntur, Andhra Pradesh, India; Department of Health, Family Welfare, and Medical Education, Government of Andhra Pradesh, Amaravati, Andhra Pradesh, India; Health and Family Welfare Department, Government of Tamil Nadu, Chennai, Tamil Nadu, India; D...
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Laxminarayan R.,Wahl B.,Dudala S.R.,et al. Epidemiology and transmission dynamics of COVID-19 in two Indian states[J],2020,370(6517).
APA Laxminarayan R..,Wahl B..,Dudala S.R..,Gopal K..,Mohan C.B..,...&Lewnard J.A..(2020).Epidemiology and transmission dynamics of COVID-19 in two Indian states.Science,370(6517).
MLA Laxminarayan R.,et al."Epidemiology and transmission dynamics of COVID-19 in two Indian states".Science 370.6517(2020).
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