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DOI | 10.1126/science.aau6299 |
Measles and the canonical path to elimination | |
Graham M.; Winter A.K.; Ferrari M.; Grenfell B.; Moss W.J.; Azman A.S.; Metcalf C.J.E.; Lessler J. | |
发表日期 | 2019 |
ISSN | 0036-8075 |
起始页码 | 584 |
结束页码 | 587 |
卷号 | 364期号:6440 |
英文摘要 | All World Health Organization regions have set measles elimination goals. We find that as countries progress toward these goals, they undergo predictable changes in the size and frequency of measles outbreaks. A country's position on this "canonical path" is driven by both measles control activities and demographic factors, which combine to change the effective size of the measles-susceptible population, thereby driving the country through theoretically established dynamic regimes. Further, position on the path to elimination provides critical information for guiding vaccination efforts, such as the age profile of susceptibility, that could only otherwise be obtained through costly field studies or sophisticated analysis. Equipped with this information, countries can gain insight into their current and future measles epidemiology and select appropriate strategies to more quickly achieve elimination goals. © 2019 American Association for the Advancement of Science. All rights reserved. |
英文关键词 | age structure; disease treatment; epidemiology; guideline; health risk; measles; vaccination; World Health Organization; age; Article; birth rate; geographic distribution; human; infection sensitivity; measles; population; priority journal; socioeconomics; vaccination; viral clearance; virus transmission; child; demography; disease eradication; disease predisposition; global health; measles; procedures; World Health Organization; measles vaccine; Child; Demography; Disease Eradication; Disease Susceptibility; Global Health; Humans; Measles; Measles Vaccine; Vaccination; World Health Organization |
语种 | 英语 |
来源期刊 | Science
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文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/243850 |
作者单位 | Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States; Department of Biology, Pennsylvania State University, University Park, PA, United States; Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, United States; Fogarty International Center, National Institutes of Health, Bethesda, MD, United States |
推荐引用方式 GB/T 7714 | Graham M.,Winter A.K.,Ferrari M.,et al. Measles and the canonical path to elimination[J],2019,364(6440). |
APA | Graham M..,Winter A.K..,Ferrari M..,Grenfell B..,Moss W.J..,...&Lessler J..(2019).Measles and the canonical path to elimination.Science,364(6440). |
MLA | Graham M.,et al."Measles and the canonical path to elimination".Science 364.6440(2019). |
条目包含的文件 | 条目无相关文件。 |
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