气候变化领域集成服务门户(CCPortal): Pixel-based open-space microfluidics for versatile surface processing

CCPortal

DOI	10.1073/pnas.2019248118
	Pixel-based open-space microfluidics for versatile surface processing
	Goyette P.-A.; Boulais É.; Tremblay M.; Gervais T.
发表日期	2021
ISSN	00278424
卷号	118 期号:2
英文摘要	An increasing number of applications in biology, chemistry, and material sciences require fluid manipulation beyond what is possible with current automated pipette handlers, such as gradient generation, interface reactions, reagent streaming, and reconfigurability. In this article, we introduce the pixelated chemical display (PCD), a scalable strategy for highly parallel, reconfigurable liquid handling on open surfaces. Microfluidic “pixels” are created when a fluid stream injected above a surface is confined by neighboring identical fluid streams, forming a repeatable flow unit that can be used to tesselate a surface. PCDs generating up to 144 pixels are fabricated and used to project “chemical moving pictures” made of several reagents over both immersed and dry surfaces, without any physical barrier or wall. This work distinguishes itself from previous work in open-space microfluidics by presenting a device architecture where the number of confinement areas can be scaled to any size. Furthermore, it challenges the open-space tenet that the aspiration rate must be higher than the injection rate for reagents to be confined. Overall, this article sets the foundation for massively parallel surface processing using continuous flow streams and showcases possibilities in both wet and dry surface patterning and roll-to-roll processes. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Microfluidics; Open-space microfluidics; Surface processing
语种	英语
scopus关键词	Article; controlled study; flow rate; microfluidics; Monte Carlo method; priority journal; signal processing
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/181062
作者单位	Institut de Génie Biomédical, Polytechnique Montréal, Montréal, QC H3T 1J4, Canada; Department of Engineering Physics, École Polytechnique de Montréal, Montréal, QC H3T 1J4, Canada; Institut du Cancer de Montréal, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, QC H2X 0C1, Canada
推荐引用方式 GB/T 7714	Goyette P.-A.,Boulais É.,Tremblay M.,et al. Pixel-based open-space microfluidics for versatile surface processing[J],2021,118(2).
APA	Goyette P.-A.,Boulais É.,Tremblay M.,&Gervais T..(2021).Pixel-based open-space microfluidics for versatile surface processing.Proceedings of the National Academy of Sciences of the United States of America,118(2).
MLA	Goyette P.-A.,et al."Pixel-based open-space microfluidics for versatile surface processing".Proceedings of the National Academy of Sciences of the United States of America 118.2(2021).