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DOI10.1073/pnas.2018043118
Cellular autofluorescence is magnetic field sensitive
Ikeya N.; Woodward J.R.
发表日期2021
ISSN00278424
卷号118期号:3
英文摘要We demonstrate, by direct, single-cell imaging kinetic measurements, that endogenous autofluorescence in HeLa cells is sensitive to the application of external magnetic fields of 25 mT and less. We provide spectroscopic and mechanistic evidence that our findings can be explained in terms of magnetic field effects on photo-induced electron transfer reactions to flavins, through the radical pair mechanism. The observed magnetic field dependence is consistent with a triplet-born radical pair and a B1/2 value of 18.0 mT with a saturation value of 3.7%. © 2021 National Academy of Sciences. All rights reserved.
英文关键词Magnetic field effect | autofluorescence | flavins | radical pair mechanism | quantum biology
语种英语
scopus关键词riboflavin derivative; Article; autofluorescence imaging; biological activity; cell culture; cell kinetics; chemical reaction; chemical structure; controlled study; electron transport; HeLa cell line; human; human cell; magnetic field; microscopy; priority journal; single cell analysis; spectrofluorometry
来源期刊Proceedings of the National Academy of Sciences of the United States of America
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/180948
作者单位Graduate School of Arts and Sciences, University of Tokyo, Tokyo, 153-8902, Japan
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Ikeya N.,Woodward J.R.. Cellular autofluorescence is magnetic field sensitive[J],2021,118(3).
APA Ikeya N.,&Woodward J.R..(2021).Cellular autofluorescence is magnetic field sensitive.Proceedings of the National Academy of Sciences of the United States of America,118(3).
MLA Ikeya N.,et al."Cellular autofluorescence is magnetic field sensitive".Proceedings of the National Academy of Sciences of the United States of America 118.3(2021).
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