CCPortal
DOI10.1073/pnas.2020398118
Wireless, soft electronics for rapid, multisensor measurements of hydration levels in healthy and diseased skin
Kwon K.; Wang H.; Lim J.; Chun K.S.; Jang H.; Yoo I.; Wu D.; Chen A.J.; Gu C.G.; Lipschultz L.; Kim J.U.; Kim J.; Jeong H.; Luan H.; Park Y.; Su C.-J.; Ishida Y.; Madhvapathy S.R.; Ikoma A.; Kwak J.W.; Yang D.S.; Banks A.; Xu S.; Huang Y.; Chang J.-K.; Rogers J.A.
发表日期2021
ISSN00278424
卷号118期号:5
英文摘要Precise, quantitative measurements of the hydration status of skin can yield important insights into dermatological health and skin structure and function, with additional relevance to essential processes of thermoregulation and other features of basic physiology. Existing tools for determining skin water content exploit surrogate electrical assessments performed with bulky, rigid, and expensive instruments that are difficult to use in a repeatable manner. Recent alternatives exploit thermal measurements using soft wireless devices that adhere gently and noninvasively to the surface of the skin, but with limited operating range (∼1 cm) and high sensitivity to subtle environmental fluctuations. This paper introduces a set of ideas and technologies that overcome these drawbacks to enable high-speed, robust, long-range automated measurements of thermal transport properties via a miniaturized, multisensor module controlled by a long-range (∼10 m) Bluetooth Low Energy system on a chip, with a graphical user interface to standard smartphones. Soft contact to the surface of the skin, with almost zero user burden, yields recordings that can be quantitatively connected to hydration levels of both the epidermis and dermis, using computational modeling techniques, with high levels of repeatability and insensitivity to ambient fluctuations in temperature. Systematic studies of polymers in layered configurations similar to those of human skin, of porcine skin with known levels of hydration, and of human subjects with benchmarks against clinical devices validate the measurement approach and associated sensor hardware. The results support capabilities in characterizing skin barrier function, assessing severity of skin diseases, and evaluating cosmetic and medication efficacy, for use in the clinic or in the home. © 2021 National Academy of Sciences. All rights reserved.
英文关键词Biomedical devices; Diagnostics; Flexible electronics; Health monitoring; Wireless electronics
语种英语
来源期刊Proceedings of the National Academy of Sciences of the United States of America
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/180827
作者单位Querrey-Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, United States; School of Electrical Engineering, Korea Advanced Institute of Science and Technology, Daejeon, 34141, South Korea; Department of Civil and Environmental Engineering, Northwestern University, Evanston, IL 60208, United States; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, United States; Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, United States; Wearifi Inc., Evanston, IL 60201, United States; Electrical and Computer Engineering, University of Texas at Austin, Austin, TX 78712, United States; Department of Electrical and Computer Engineering, University of Wisconsin, Madison, WI 53706, United States; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, United States; School of Chemical Engineering, Sungkyunkwan University, Suwon, 16419, South Korea; School of Advanced Materials Sc...
推荐引用方式
GB/T 7714
Kwon K.,Wang H.,Lim J.,et al. Wireless, soft electronics for rapid, multisensor measurements of hydration levels in healthy and diseased skin[J],2021,118(5).
APA Kwon K..,Wang H..,Lim J..,Chun K.S..,Jang H..,...&Rogers J.A..(2021).Wireless, soft electronics for rapid, multisensor measurements of hydration levels in healthy and diseased skin.Proceedings of the National Academy of Sciences of the United States of America,118(5).
MLA Kwon K.,et al."Wireless, soft electronics for rapid, multisensor measurements of hydration levels in healthy and diseased skin".Proceedings of the National Academy of Sciences of the United States of America 118.5(2021).
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Kwon K.]的文章
[Wang H.]的文章
[Lim J.]的文章
百度学术
百度学术中相似的文章
[Kwon K.]的文章
[Wang H.]的文章
[Lim J.]的文章
必应学术
必应学术中相似的文章
[Kwon K.]的文章
[Wang H.]的文章
[Lim J.]的文章
相关权益政策
暂无数据
收藏/分享

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。