气候变化领域集成服务门户(CCPortal): Kin selection explains the evolution of cooperation in the gut microbiota

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DOI	10.1073/pnas.2016046118
	Kin selection explains the evolution of cooperation in the gut microbiota
	Simonet C.; McNally L.
发表日期	2021
ISSN	00278424
卷号	118 期号:6
英文摘要	Through the secretion of “public goods” molecules, microbes cooperatively exploit their habitat. This is known as a major driver of the functioning of microbial communities, including in human disease. Understanding why microbial species cooperate is therefore crucial to achieve successful microbial community management, such as microbiome manipulation. A leading explanation is that of Hamilton's inclusive-fitness framework. A cooperator can indirectly transmit its genes by helping the reproduction of an individual carrying similar genes. Therefore, all else being equal, as relatedness among individuals increases, so should cooperation. However, the predictive power of relatedness, particularly in microbes, is surrounded by controversy. Using phylogenetic comparative analyses across the full diversity of the human gut microbiota and six forms of cooperation, we find that relatedness is predictive of the cooperative gene content evolution in gut-microbe genomes. Hence, relatedness is predictive of cooperation over broad microbial taxonomic levels that encompass variation in other life-history and ecology details. This supports the generality of Hamilton's central insights and the relevance of relatedness as a key parameter of interest to advance microbial predictive and engineering science. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Comparative analysis; Cooperation; Evolutionary microbiology; Microbiome
语种	英语
scopus关键词	Article; bacterial evolution; ecology; human; intestine flora; kin selection; life history; microbial community; microbial diversity; microbial gene; microbial genome; nonhuman; phylogeny; priority journal; species habitat; taxonomy
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/180679
作者单位	Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3FL, United Kingdom; Centre for Synthetic and Systems Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom
推荐引用方式 GB/T 7714	Simonet C.,McNally L.. Kin selection explains the evolution of cooperation in the gut microbiota[J],2021,118(6).
APA	Simonet C.,&McNally L..(2021).Kin selection explains the evolution of cooperation in the gut microbiota.Proceedings of the National Academy of Sciences of the United States of America,118(6).
MLA	Simonet C.,et al."Kin selection explains the evolution of cooperation in the gut microbiota".Proceedings of the National Academy of Sciences of the United States of America 118.6(2021).