气候变化领域集成服务门户(CCPortal): Pathogen disgust sensitivity protects against infection in a high pathogen environment

CCPortal

DOI	10.1073/pnas.2018552118
	Pathogen disgust sensitivity protects against infection in a high pathogen environment
	Cepon-Robins T.J.; Blackwell A.D.; Gildner T.E.; Liebert M.A.; Urlacher S.S.; Madimenos F.C.; Eick G.N.; Josh Snodgrass J.; Sugiyama L.S.
发表日期	2021
ISSN	00278424
卷号	118 期号:8
英文摘要	Disgust is hypothesized to be an evolved emotion that functions to regulate the avoidance of pathogen-related stimuli and behaviors. Individuals with higher pathogen disgust sensitivity (PDS) are predicted to be exposed to and thus infected by fewer pathogens, though no studies have tested this directly. Furthermore, PDS is hypothesized to be locally calibrated to the types of pathogens normally encountered and the fitness-related costs and benefits of infection and avoidance. Market integration (the degree of production for and consumption from market-based economies) influences the relative costs/benefits of pathogen exposure and avoidance through sanitation, hygiene, and lifestyle changes, and is thus predicted to affect PDS. Here, we examine the function of PDS in disease avoidance, its environmental calibration, and its socioecological variation by examining associations among PDS, market-related lifestyle factors, and measures of bacterial, viral, and macroparasitic infection at the individual, household, and community levels. Data were collected among 75 participants (ages 5 to 59 y) from 28 households in three Ecuadorian Shuar communities characterized by subsistence-based lifestyles and high pathogen burden, but experiencing rapid market integration. As predicted, we found strong negative associations between PDS and biomarkers of immune response to viral/bacterial infection, and weaker associations between PDS and measures of macroparasite infection, apparently mediated by market integration-related differences. We provide support for the previously untested hypothesis that PDS is negatively associated with infection, and document variation in PDS indicative of calibration to local socioeconomic conditions. More broadly, findings highlight the importance of evolved psychological mechanisms in human health outcomes. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Behavioral immune system; Disgust; Market integration; Pathogen avoidance; Shuar
语种	英语
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/180556
作者单位	Department of Anthropology, University of Colorado, Colorado Springs, CO 80918, United States; Department of Anthropology, Washington State University, Pullman, WA 99164, United States; Department of Anthropology, Washington University in St. Louis, St. Louis, MO 63130, United States; Department of Anthropology, Northern Arizona University, Flagstaff, AZ 86011, United States; Department of Anthropology, Baylor University, Waco, TX 76706, United States; Child and Brain Development Program, Canadian Institute for Advanced Research, Toronto, ON M5G 1M1, Canada; Department of Anthropology, Queens College, City University of New York, Queens, NY 11367, United States; Department of Anthropology, University of Oregon, Eugene, OR 97403, United States; Center for Global Health, University of Oregon, Eugene, OR 97403, United States
推荐引用方式 GB/T 7714	Cepon-Robins T.J.,Blackwell A.D.,Gildner T.E.,et al. Pathogen disgust sensitivity protects against infection in a high pathogen environment[J],2021,118(8).
APA	Cepon-Robins T.J..,Blackwell A.D..,Gildner T.E..,Liebert M.A..,Urlacher S.S..,...&Sugiyama L.S..(2021).Pathogen disgust sensitivity protects against infection in a high pathogen environment.Proceedings of the National Academy of Sciences of the United States of America,118(8).
MLA	Cepon-Robins T.J.,et al."Pathogen disgust sensitivity protects against infection in a high pathogen environment".Proceedings of the National Academy of Sciences of the United States of America 118.8(2021).