气候变化领域集成服务门户(CCPortal): Attention recruits frontal cortex in human infants

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DOI	10.1073/pnas.2021474118
	Attention recruits frontal cortex in human infants
	Ellis C.T.; Skalaban L.J.; Yates T.S.; Turk-Browne N.B.
发表日期	2021
ISSN	00278424
卷号	118 期号:12
英文摘要	Young infants learn about the world by overtly shifting their attention to perceptually salient events. In adults, attention recruits several brain regions spanning the frontal and parietal lobes. However, it is unclear whether these regions are sufficiently mature in infancy to support attention and, more generally, how infant attention is supported by the brain. We used event-related functional magnetic resonance imaging (fMRI) in 24 sessions from 20 awake behaving infants 3 mo to 12 mo old while they performed a child-friendly attentional cuing task. A target was presented to either the left or right of the infant’s fixation, and offline gaze coding was used to measure the latency with which they saccaded to the target. To manipulate attention, a brief cue was presented before the target in three conditions: on the same side as the upcoming target (valid), on the other side (invalid), or on both sides (neutral). All infants were faster to look at the target on valid versus invalid trials, with valid faster than neutral and invalid slower than neutral, indicating that the cues effectively captured attention. We then compared the fMRI activity evoked by these trial types. Regions of adult attention networks activated more strongly for invalid than valid trials, particularly frontal regions. Neither behavioral nor neural effects varied by infant age within the first year, suggesting that these regions may function early in development to support the orienting of attention. Together, this furthers our mechanistic understanding of how the infant brain controls the allocation of attention. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Attentional cuing; Early development; FMRI; Frontoparietal network; Gaze coding
语种	英语
scopus关键词	adult; article; attention network; child; clinical article; controlled study; female; frontal cortex; frontoparietal network; functional magnetic resonance imaging; gaze; human; human experiment; infant; male; wakefulness; functional magnetic resonance imaging
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/180175
作者单位	Department of Psychology, Yale University, New Haven, CT 06511, United States
推荐引用方式 GB/T 7714	Ellis C.T.,Skalaban L.J.,Yates T.S.,et al. Attention recruits frontal cortex in human infants[J],2021,118(12).
APA	Ellis C.T.,Skalaban L.J.,Yates T.S.,&Turk-Browne N.B..(2021).Attention recruits frontal cortex in human infants.Proceedings of the National Academy of Sciences of the United States of America,118(12).
MLA	Ellis C.T.,et al."Attention recruits frontal cortex in human infants".Proceedings of the National Academy of Sciences of the United States of America 118.12(2021).