气候变化领域集成服务门户(CCPortal): Associations between adolescent cannabis use and young-adult functioning in three longitudinal twin studies

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DOI	10.1073/pnas.2013180118
	Associations between adolescent cannabis use and young-adult functioning in three longitudinal twin studies
	Schaefer J.D.; Hamdi N.R.; Malone S.M.; Vrieze S.; Wilson S.; McGue M.; Iacono W.G.
发表日期	2021
ISSN	00278424
卷号	118 期号:14
英文摘要	Observational studies have linked cannabis use to an array of negative outcomes, including psychiatric symptoms, cognitive impairment, and educational and occupational underachievement. These associations are particularly strong when cannabis use occurs in adolescence. Nevertheless, causality remains unclear. The purpose of the present study was thus to examine associations between prospectively assessed adolescent cannabis use and young-adult outcomes (psychiatric, cognitive, and socioeconomic) in three longitudinal studies of twins (n = 3,762). Twins reporting greater cumulative cannabis use in adolescence reported higher levels of psychopathology as well as poorer socioeconomic outcomes in young adulthood. However, cannabis use remained associated only with socioeconomic outcomes (i.e., educational attainment, occupational status, and income) in monozygotic-cotwin control analyses, which account fully for shared genetic and environmental confounding. Follow-up analyses examining associations between twin differences in adolescent cannabis use and longitudinal change in academic functioning during the middle- and high-school years provided a possible mechanism for these associations, indicating that greater cannabis use during this period was associated with decreases in grade point average and academic motivation as well as increases in academic problem behavior and school disciplinary problems. Our findings thus suggest that cannabis use in adolescence has potentially causal, deleterious effects on adolescent academic functioning and youngadult socioeconomic outcomes despite little evidence suggesting a strong, causal influence on adult mental health or cognitive ability. © 2021 National Academy of Sciences. All rights reserved.
英文关键词	Adolescence; Cannabis; Education; Marijuana; Twin
语种	英语
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/179984
作者单位	Institute of Child Development, University of Minnesota, Minneapolis, MN 55455, United States; Northwest Metro VA Clinic, Minneapolis Veterans Affairs Health Care System, Ramsey, MN 55303, United States; Department of Psychology, University of Minnesota, Minneapolis, MN 55455, United States
推荐引用方式 GB/T 7714	Schaefer J.D.,Hamdi N.R.,Malone S.M.,et al. Associations between adolescent cannabis use and young-adult functioning in three longitudinal twin studies[J],2021,118(14).
APA	Schaefer J.D..,Hamdi N.R..,Malone S.M..,Vrieze S..,Wilson S..,...&Iacono W.G..(2021).Associations between adolescent cannabis use and young-adult functioning in three longitudinal twin studies.Proceedings of the National Academy of Sciences of the United States of America,118(14).
MLA	Schaefer J.D.,et al."Associations between adolescent cannabis use and young-adult functioning in three longitudinal twin studies".Proceedings of the National Academy of Sciences of the United States of America 118.14(2021).