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DOI10.4274/mirt.galenos.2020.31932
Correlation between perfusion abnormalities extent in ventilation/ perfusion spect/ct with hemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension [Kronik tromboembolik pulmoner hipertansiyonlu hastalarda ventilasyon/perfüzyon spect/bt’de saptanan perfüzyon defekti yaygınlığı ile hemodinamik parametreler arasındaki ilişki]
Özgüven S.; Kesim S.; Öksüzoğlu K.; Yanartaş M.; Taş S.; Şen F.; Öneş T.; İnanır S.; Turoğlu H.T.; Mutlu B.; Erdil T.Y.; Yıldızeli B.
发表日期2021
ISSN21461414
起始页码28
结束页码33
卷号30期号:1
英文摘要Objectives: Chronic thromboembolic pulmonary hypertension (CTEPH) is a type of pulmonary hypertension with persistent pulmonary vascular obstruction and exercise intolerance, which may benefit from pulmonary endarterectomy (PEA). Ventilation/perfusion (V/Q) scan is the preferred screening test of CTEPH, which can be used to assess the anatomical extent of the disease. This study aimed to analyze the correlation between the extent of mismatched Q defects in V/Q single photon emission computed tomography/computed tomography (SPECT/CT) with preoperative clinical and hemodynamic parameters in patients with CTEPH. Methods: A total of 102 patients with CTEPH prior to PEA having V/Q SPECT/CT scans were retrospectively reviewed. Age, gender, New York Heart Association classification, intraoperative right-sided heart catheterization (mPAP and PVR), and 6-minute walk test (6MWT) findings were obtained from clinical records of patients. Results: Linear regression analysis showed a significant but weak correlation between the preoperative mPAP and PVR with the extent of mismatched Q defects in V/Q SPECT/CT (rs=0.09474 with p=0.0016 and rs=0.045 with p=0.045, respectively). No significant correlation was found between 6MWT and extent of mismatched Q defects in V/Q SPECT/CT (p>0.05). Conclusion: A quantitative assessment of Q defects on V/Q SPECT/CT might provide information about hemodynamic parameters in patients with CTEPH. © 2021 by Turkish Society of Nuclear Medicine.
英文关键词6-minute walk distance; Chronic thromboembolic pulmonary hypertension; Mean pulmonary arterial pressure; Pulmonary vascular resistance; Ventilation/perfusion scintigraphy
scopus关键词albumin; technegas; technetium 99m; adult; age; aged; Article; artificial ventilation; blood vessel occlusion; correlation analysis; disease severity; echinococcosis; endarterectomy; female; gender; heart catheterization; hemodynamic parameters; human; image analysis; image reconstruction; lung artery pressure; lung vascular resistance; major clinical study; male; New York Heart Association class; preoperative evaluation; retrospective study; screening test; single photon emission computed tomography; six minute walk test; ventilation-perfusion scan
来源期刊Molecular Imaging and Radionuclide Therapy
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/177258
作者单位Marmara University Pendik Training and Research Hospital, Clinic of Nuclear Medicine, İstanbul, Turkey; University of Health Sciences Turkey, Kartal Koşuyolu Training and Research Hospital, Clinic of Cardiovascular Surgery, İstanbul, Turkey; Marmara University Pendik Training and Research Hospital, Clinic of Cardiology, İstanbul, Turkey; Marmara University Pendik Training and Research Hospital, Clinic of Thoracic Surgery, İstanbul, Turkey
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Özgüven S.,Kesim S.,Öksüzoğlu K.,等. Correlation between perfusion abnormalities extent in ventilation/ perfusion spect/ct with hemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension [Kronik tromboembolik pulmoner hipertansiyonlu hastalarda ventilasyon/perfüzyon spect/bt’de saptanan perfüzyon defekti yaygınlığı ile hemodinamik parametreler arasındaki ilişki][J],2021,30(1).
APA Özgüven S..,Kesim S..,Öksüzoğlu K..,Yanartaş M..,Taş S..,...&Yıldızeli B..(2021).Correlation between perfusion abnormalities extent in ventilation/ perfusion spect/ct with hemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension [Kronik tromboembolik pulmoner hipertansiyonlu hastalarda ventilasyon/perfüzyon spect/bt’de saptanan perfüzyon defekti yaygınlığı ile hemodinamik parametreler arasındaki ilişki].Molecular Imaging and Radionuclide Therapy,30(1).
MLA Özgüven S.,et al."Correlation between perfusion abnormalities extent in ventilation/ perfusion spect/ct with hemodynamic parameters in patients with chronic thromboembolic pulmonary hypertension [Kronik tromboembolik pulmoner hipertansiyonlu hastalarda ventilasyon/perfüzyon spect/bt’de saptanan perfüzyon defekti yaygınlığı ile hemodinamik parametreler arasındaki ilişki]".Molecular Imaging and Radionuclide Therapy 30.1(2021).
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