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DOI10.5194/acp-20-15775-2020
Effects of AIR pollution on cardiopuLmonary disEaSe in urban and peri-urban reSidents in Beijing: Protocol for the AIRLESS study
Han Y.; Chen W.; Chatzidiakou L.; Krause A.; Yan L.; Zhang H.; Chan Q.; Barratt B.; Jones R.; Liu J.; Wu Y.; Zhao M.; Zhang J.; Kelly F.J.; Zhu T.
发表日期2020
ISSN1680-7316
起始页码15775
结束页码15792
卷号20期号:24
英文摘要

Beijing, as a representative megacity in China, is experiencing some of the most severe air pollution episodes in the world, and its fast urbanization has led to substantial urban and peri-urban disparities in both health status and air quality. Uncertainties remain regarding the possible causal links between individual air pollutants and health outcomes, with spatial comparative investigations of these links lacking, particularly in developing megacities. In light of this challenge, Effects of AIR pollution on cardiopuLmonary disEaSe in urban and peri-urban reSidents in Beijing (AIRLESS) was initiated, with the aim of addressing the complex issue of relating multi-pollutant exposure to cardiopulmonary outcomes. This paper presents the novel methodological framework employed in the project, namely (1) the deployment of two panel studies from established cohorts in urban and peri-urban Beijing, with different exposure settings regarding pollution levels and diverse sources; (2) the collection of detailed measurements and biomarkers of participants from a nested case (hypertensive) and control (healthy) study setting; (3) the assessment of indoor and personal exposure to multiple gaseous pollutants and particulate matter at unprecedented spatial and temporal resolution with validated novel sensor technologies; (4) the assessment of ambient air pollution levels in a large-scale field campaign, particularly the chemical composition of particulate matter. Preliminary results showed that there is a large difference between ambient and personal air pollution levels, and the differences varied between seasons and locations. These large differences were reflected on the different health responses between the two panels.

. © 2020 Institute of Electrical and Electronics Engineers Inc.. All rights reserved.
英文关键词atmospheric pollution; biomarker; cardiovascular disease; cohort analysis; particulate matter; periurban area; pollution effect; pollution exposure; respiratory disease; urban area; Beijing [Beijing (ADS)]; Beijing [China]; China
语种英语
来源期刊Atmospheric Chemistry and Physics
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/168875
作者单位BIC-ESAT and SKL-ESPC, College of Environmental Sciences and Engineering, Peking University, Beijing, 100871, China; Environmental Research Group, MRC Centre for Environment and Health, Imperial College London, London, United Kingdom; Centre for Atmospheric Science, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom; Department of Epidemiology and Biostatistics, MRC Centre for Environment and Health, Imperial College London, London, United Kingdom; Department of Epidemiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China; Peking University, Clinical Research Institute, Beijing, China; The George Institute for Global Health, Peking University, Health Science Center, Beijing, China; College of Chemistry, Peking University, Beijing, China; Duke Global Health Institute, Duke Kunshan University, Nanjing, China
推荐引用方式
GB/T 7714
Han Y.,Chen W.,Chatzidiakou L.,et al. Effects of AIR pollution on cardiopuLmonary disEaSe in urban and peri-urban reSidents in Beijing: Protocol for the AIRLESS study[J],2020,20(24).
APA Han Y..,Chen W..,Chatzidiakou L..,Krause A..,Yan L..,...&Zhu T..(2020).Effects of AIR pollution on cardiopuLmonary disEaSe in urban and peri-urban reSidents in Beijing: Protocol for the AIRLESS study.Atmospheric Chemistry and Physics,20(24).
MLA Han Y.,et al."Effects of AIR pollution on cardiopuLmonary disEaSe in urban and peri-urban reSidents in Beijing: Protocol for the AIRLESS study".Atmospheric Chemistry and Physics 20.24(2020).
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