气候变化领域集成服务门户(CCPortal): Genome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation

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DOI	10.1073/pnas.2018123117
	Genome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation
	Li K.; Zhang S.; Song X.; Weyrich A.; Wang Y.; Liu X.; Wan N.; Liu J.; Lovy M.; Cui H.; Frenkel V.; Titievsky A.; Panov J.; Brodsky L.; Nevo E.
发表日期	2020
ISSN	0027-8424
起始页码	32499
结束页码	32508
卷号	117 期号:51
英文摘要	Speciation mechanisms remain controversial. Two speciation models occur in Israeli subterranean mole rats, genus Spalax: a regional speciation cline southward of four peripatric climatic chromosomal species and a local, geologic-edaphic, genic, and sympatric speciation. Here we highlight their genome evolution. The five species were separated into five genetic clusters by single nucleotide polymorphisms, copy number variations (CNVs), repeatome, and methylome in sympatry. The regional interspecific divergence correspond to Pleistocene climatic cycles. Climate warmings caused chromosomal speciation. Triple effective population size, Ne, declines match glacial cold cycles. Adaptive genes evolved under positive selection to underground stresses and to divergent climates, involving interspecies reproductive isolation. Genomic islands evolved mainly due to adaptive evolution involving ancient polymorphisms. Repeatome, including both CNV and LINE1 repetitive elements, separated the five species. Methylation in sympatry identified geologically chalk-basalt species that differentially affect thermoregulation, hypoxia, DNA repair, P53, and other pathways. Genome adaptive evolution highlights climatic and geologic-edaphic stress evolution and the two speciation models, peripatric and sympatric. © 2020 National Academy of Sciences. All rights reserved.
英文关键词	Genomic sequencing; Methylation; Repeatome; Speciation models; Subterranean rodents
语种	英语
scopus关键词	protein p53; animal experiment; Article; climate warming; cold; copy number variation; DNA repair; evolution; gene; gene cluster; genomic island; hypoxia; mole rat; nonhuman; Pleistocene; population size; priority journal; rat; separation technique; sequence analysis; signal transduction; single nucleotide polymorphism; species differentiation; thermoregulation
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/160680
作者单位	Li, K., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou University, Lanzhou, 730000, China, Institute of Evolution, University of Haifa, Haifa, 3498838, Israel; Zhang, S., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou University, Lanzhou, 730000, China; Song, X., School of Public Health, Lanzhou University, Lanzhou, 730000, China; Weyrich, A., Leibniz Institute for Zoo and Wildlife Research, Berlin, 10315, Germany; Wang, Y., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou University, Lanzhou, 730000, China; Liu, X., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou University, Lanzhou, 730000, China; Wan, N., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou University, Lanzhou, 730000, China; Liu, J., State Key Laboratory of Grassland Agro-Ecosystem, Institute of Innovation Ecology, Lanzhou Univ...
推荐引用方式 GB/T 7714	Li K.,Zhang S.,Song X.,et al. Genome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation[J],2020,117(51).
APA	Li K..,Zhang S..,Song X..,Weyrich A..,Wang Y..,...&Nevo E..(2020).Genome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation.Proceedings of the National Academy of Sciences of the United States of America,117(51).
MLA	Li K.,et al."Genome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation".Proceedings of the National Academy of Sciences of the United States of America 117.51(2020).