气候变化领域集成服务门户(CCPortal): Noncanonical auxin signaling regulates cell division pattern during lateral root development

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DOI	10.1073/pnas.1910916116
	Noncanonical auxin signaling regulates cell division pattern during lateral root development
	Huang R.; Zheng R.; He J.; Zhou Z.; Wang J.; Xiong Y.; Xu T.
发表日期	2019
ISSN	0027-8424
起始页码	21285
结束页码	21290
卷号	116 期号:42
英文摘要	In both plants and animals, multiple cellular processes must be orchestrated to ensure proper organogenesis. The cell division patterns control the shape of growing organs, yet how they are precisely determined and coordinated is poorly understood. In plants, the distribution of the phytohormone auxin is tightly linked to organogenesis, including lateral root (LR) development. Nevertheless, how auxin regulates cell division pattern during lateral root development remains elusive. Here, we report that auxin activates Mitogen-Activated Protein Kinase (MAPK) signaling via transmembrane kinases (TMKs) to control cell division pattern during lateral root development. Both TMK1/4 and MKK4/5-MPK3/6 pathways are required to properly orient cell divisions, which ultimately determine lateral root development in response to auxin. We show that TMKs directly and specifically interact with and phosphorylate MKK4/5, which is required for auxin to activate MKK4/5-MPK3/6 signaling. Our data suggest that TMK-mediated noncanonical auxin signaling is required to regulate cell division pattern and connect auxin signaling to MAPK signaling, which are both essential for plant development. © 2019 National Academy of Sciences. All rights reserved.
英文关键词	Auxin; Cell division pattern; MKK4/5; MPK3/6; TMKs
语种	英语
scopus关键词	auxin; mitogen activated protein kinase kinase 3; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 5; mitogen activated protein kinase kinase 6; Arabidopsis protein; indoleacetic acid derivative; mitogen activated protein kinase; mitogen activated protein kinase kinase; Article; cell division; controlled study; down regulation; gene switching; lateral root; MAPK signaling; membrane potential; MKK3 gene; MKK4 gene; MKK5 gene; MKK6 gene; nonhuman; organogenesis; plant development; priority journal; protein expression; protein phosphorylation; protein protein interaction; root development; signal transduction; transcription regulation; upregulation; Arabidopsis; cell division; gene expression regulation; genetics; metabolism; phosphorylation; plant organogenesis; plant root; signal transduction; Arabidopsis; Arabidopsis Proteins; Cell Division; Gene Expression Regulation, Plant; Indoleacetic Acids; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Organogenesis, Plant; Phosphorylation; Plant Development; Plant Roots; Signal Transduction
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/160339
作者单位	Huang, R., Horticulture Biology and Metabolomics Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China; Zheng, R., Shanghai Center for Plant Stress Biology, Center for Excellence in Molecular Plant Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 201602, China, University of Chinese Academy of Sciences, Beijing, 100049, China; He, J., Horticulture Biology and Metabolomics Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China; Zhou, Z., Temasek Life Science Laboratory Ltd., National University of Singapore117604, Singapore; Wang, J., Horticulture Biology and Metabolomics Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China; Xiong, Y., Horticulture Biology and Metabolomics Center, Haixia Institute of Science and Technology, Fujian Agriculture and For...
推荐引用方式 GB/T 7714	Huang R.,Zheng R.,He J.,et al. Noncanonical auxin signaling regulates cell division pattern during lateral root development[J],2019,116(42).
APA	Huang R..,Zheng R..,He J..,Zhou Z..,Wang J..,...&Xu T..(2019).Noncanonical auxin signaling regulates cell division pattern during lateral root development.Proceedings of the National Academy of Sciences of the United States of America,116(42).
MLA	Huang R.,et al."Noncanonical auxin signaling regulates cell division pattern during lateral root development".Proceedings of the National Academy of Sciences of the United States of America 116.42(2019).