气候变化领域集成服务门户(CCPortal): Late lactation in small mammals is a critically sensitive window of vulnerability to elevated ambient temperature

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DOI	10.1073/pnas.2008974117
	Late lactation in small mammals is a critically sensitive window of vulnerability to elevated ambient temperature
	Zhao Z.-J.; Hambly C.; Shi L.-L.; Bi Z.-Q.; Cao J.; Speakman J.R.
发表日期	2020
ISSN	0027-8424
起始页码	24352
结束页码	24358
卷号	117 期号:39
英文摘要	Predicted increases in global average temperature are physiologically trivial for most endotherms. However, heat waves will also increase in both frequency and severity, and these will be physiologically more important. Lactating small mammals are hypothesized to be limited by heat dissipation capacity, suggesting high temperatures may adversely impact lactation performance. We measured reproductive performance of mice and striped hamsters (Cricetulus barabensis), including milk energy output (MEO), at temperatures between 21 and 36 °C. In both species, there was a decline in MEO between 21 and 33 °C. In mice, milk production at 33 °C was only 18% of that at 21 °C. This led to reductions in pup growth by 20% but limited pup mortality (0.8%), because of a threefold increase in growth efficiency. In contrast, in hamsters, MEO at 33 °C was reduced to 78.1% of that at 21 °C, yet this led to significant pup mortality (possibly infanticide) and reduced pup growth by 12.7%. Hamster females were more able to sustain milk production as ambient temperature increased, but they and their pups were less capable of adjusting to the lower supply. In both species, exposure to 36 °C resulted in rapid catastrophic lactation failure and maternal mortality. Upper lethal temperature was lowered by 3 to 6 °C in late lactation, making it a critically sensitive window to high ambient temperatures. Our data suggest future heat wave events will impact breeding success of small rodents, but this is based on animals with a long history in captivity. More work should be performed on wild rodents to confirm these impacts. © 2020 National Academy of Sciences. All rights reserved.
英文关键词	Climate change; Energetics; Heat waves; Lactation; Lethal temperature
语种	英语
scopus关键词	animal experiment; article; breeding success; climate change; controlled study; Cricetulus; environmental temperature; female; heat wave; high temperature; infanticide; lactation; maternal mortality; milk production; mouse; nonhuman; reproductive success; small mammal
来源期刊	Proceedings of the National Academy of Sciences of the United States of America
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/160218
作者单位	Zhao, Z.-J., School of Life and Environmental Sciences, Wenzhou University, Wenzhou, Zhejiang, 325035, China; Hambly, C., Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, AB39 2PN, United Kingdom; Shi, L.-L., School of Life and Environmental Sciences, Wenzhou University, Wenzhou, Zhejiang, 325035, China; Bi, Z.-Q., School of Life and Environmental Sciences, Wenzhou University, Wenzhou, Zhejiang, 325035, China; Cao, J., School of Life and Environmental Sciences, Wenzhou University, Wenzhou, Zhejiang, 325035, China; Speakman, J.R., Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, AB39 2PN, United Kingdom, State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences (CAS), Beijing, 100100, China, CAS Center of Excellence for Animal Evolution and Genetics, Kunming, 650223, China
推荐引用方式 GB/T 7714	Zhao Z.-J.,Hambly C.,Shi L.-L.,et al. Late lactation in small mammals is a critically sensitive window of vulnerability to elevated ambient temperature[J],2020,117(39).
APA	Zhao Z.-J.,Hambly C.,Shi L.-L.,Bi Z.-Q.,Cao J.,&Speakman J.R..(2020).Late lactation in small mammals is a critically sensitive window of vulnerability to elevated ambient temperature.Proceedings of the National Academy of Sciences of the United States of America,117(39).
MLA	Zhao Z.-J.,et al."Late lactation in small mammals is a critically sensitive window of vulnerability to elevated ambient temperature".Proceedings of the National Academy of Sciences of the United States of America 117.39(2020).