气候变化领域集成服务门户(CCPortal): Identification and genomic features of halotolerant extended-spectrum-β-lactamase (CTX-M)-producing Escherichia coli in urban-impacted coastal waters; Southeast Brazil

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DOI	10.1016/j.marpolbul.2019.110689
	Identification and genomic features of halotolerant extended-spectrum-β-lactamase (CTX-M)-producing Escherichia coli in urban-impacted coastal waters; Southeast Brazil
	Fernandes M.R.; Sellera F.P.; Moura Q.; Esposito F.; Sabino C.P.; Lincopan N.
发表日期	2020
ISSN	0025326X
卷号	150
英文摘要	We report the occurrence and genomic analysis of extended-spectrum β-lactamase (CTX-M)-producing Escherichia coli in anthropogenically polluted coastal waters of Southeast Brazil. E. coli strains belonging to sequence types (STs) ST10, ST38, ST155 and ST1284 exhibited a wide resistome, with genes conferring resistance to medically relevant antimicrobials and heavy metals, and a halophilic behavior (tolerance to 9–10% NaCl). These findings suggest a heavy contamination in this area by critical priority bacteria adapted to marine environments, which might have negative impacts on human and ocean health. © 2019 Elsevier Ltd
英文关键词	Aquatic environment; Beach; Enterobacteriaceae; ESBL; MDR bacteria
语种	英语
scopus关键词	Beaches; Genes; Heavy metals; Marine pollution; Sodium chloride; Aquatic environments; Coastal waters; Enterobacteriaceae; ESBL; Genomic analysis; Halotolerant; Marine environment; Southeast Brazil; Escherichia coli; aminoglycoside antibiotic agent; beta lactam antibiotic; chloramphenicol; cotrimoxazole; heavy metal; quinoline derived antiinfective agent; sodium chloride; beta lactamase; sea water; anthropogenic source; aquatic environment; beach; coastal water; coliform bacterium; enzyme activity; genomics; identification method; pollution tolerance; antibiotic resistome; bacterium identification; Brazil; coastal waters; evolutionary adaptation; extended spectrum beta lactamase producing Escherichia coli; gene sequence; genomics; nonhuman; salt tolerance; sea pollution; urban area; environmental monitoring; Escherichia coli; Escherichia coli infection; genomics; human; isolation and purification; metabolism; microbiology; physiology; salt tolerance; Brazil; Enterobacteriaceae; Escherichia coli; beta-Lactamases; Brazil; Environmental Monitoring; Escherichia coli; Escherichia coli Infections; Genomics; Humans; Salt Tolerance; Seawater; Water Microbiology
来源期刊	Marine Pollution Bulletin
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/149411
作者单位	Department of Clinical Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil; Department of Internal Medicine, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil; Faculty of Health Sciences, Federal University of Grande DouradosMato Grosso do Sul, Brazil; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil
推荐引用方式 GB/T 7714	Fernandes M.R.,Sellera F.P.,Moura Q.,et al. Identification and genomic features of halotolerant extended-spectrum-β-lactamase (CTX-M)-producing Escherichia coli in urban-impacted coastal waters; Southeast Brazil[J],2020,150.
APA	Fernandes M.R.,Sellera F.P.,Moura Q.,Esposito F.,Sabino C.P.,&Lincopan N..(2020).Identification and genomic features of halotolerant extended-spectrum-β-lactamase (CTX-M)-producing Escherichia coli in urban-impacted coastal waters; Southeast Brazil.Marine Pollution Bulletin,150.
MLA	Fernandes M.R.,et al."Identification and genomic features of halotolerant extended-spectrum-β-lactamase (CTX-M)-producing Escherichia coli in urban-impacted coastal waters; Southeast Brazil".Marine Pollution Bulletin 150(2020).